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人参皂苷对恶性脑胶质瘤细胞BT325增殖的影响
引用本文:罗俊生,张齐,关宁,霍小川. 人参皂苷对恶性脑胶质瘤细胞BT325增殖的影响[J]. 辽宁中医杂志, 2006, 33(10): 1319-1320
作者姓名:罗俊生  张齐  关宁  霍小川
作者单位:1. 锦州医学院第一附属医院,辽宁,锦州,121001
2. 锦州医学院第二附属医院,辽宁,锦州,121001
摘    要:目的:探索人参皂苷对恶性脑胶质瘤细胞BT325的作用。方法:MTT法测定人参皂苷对恶性脑胶质瘤细胞(BT325)增殖的影响,采用流式细胞仪检测其对恶性脑胶质瘤细胞(BT325)周期的影响。结果:10~100μg/mL人参皂苷可抑制恶性脑胶质瘤细胞(BT325)增殖,流式细胞仪检测人参皂苷阻止恶性脑胶质瘤细胞(BT325)在G1/S期。结论:人参皂苷对恶性脑胶质瘤细胞(BT325)增殖具有抑制作用。

关 键 词:人参皂苷  恶性脑胶质瘤  BT325
文章编号:1000-1719(2006)10-1319-02
收稿时间:2006-07-03
修稿时间:2006-07-03

Effection of Ginsenoside on Malignant Glioma Cell BT325 Proliferation
Luo Junsheng,Zhang Qi,Guan Ning,Huo Xiaochuan. Effection of Ginsenoside on Malignant Glioma Cell BT325 Proliferation[J]. Liaoning Journal of Traditional Chinese Medicine, 2006, 33(10): 1319-1320
Authors:Luo Junsheng  Zhang Qi  Guan Ning  Huo Xiaochuan
Affiliation:1. The First Affiliated Hospital of Jinzhou Medical College, Jinzhou 121001, Liaoning, China; 2. The Second Hospital Attached to Jinzhou Medical College, Jinzhou 121001, Liaoning, China
Abstract:Objective: To explore the effection of GS on malignant gliomacell BT325.Methods:MTT was adopted to evaluate the effect of GS on malignant gliomacell BT325 proliferation;Flow cytometrywas adopted to detecte the effect of GS on BT325cellcycle.Results:10-100μg/mL GS obviosly inhibited the proliferation of BT325cell,GS could blockBT325cellin G_(1)/S phase by Flow cytometry.Conclusions:RCG could effectively inhibite the BT325cell proliferation.
Keywords:ginsenoside  malignant glioma  BT325
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