298例儿童呼吸系统疾病抗菌药物应用情况探究

目的 了解本地区儿科呼吸系统疾病抗菌药物的应用现状,探寻行之有效的管理和干预办法.方法 收集2017年12月至2019年1月间于宿迁市中医院就诊的298例呼吸系统疾病患儿的就诊资料,并加以分析.结果 298例患儿中,急性上呼吸道感染抗菌药物使用率占63.2％,气管支气管炎抗菌药物使用率达83.9％,差异有统计学意义(P...

Investigation into the use of antibiotics in the treatment of 298 children with respiratory diseases

Objective To investigate the application of antibacterial medicines in pediatric respiratory diseases to search for effective ways of management and intervention.Methods The medical records of 298 children with respiratory diseases treated in Suqian TCM Hospital from December 2017 to January 2019 were collected and analyzed.Results Among the 298 cases,the utilization rate of antibiotics in children with acute upper respiratory tract infection was 63.2%,and that in children with tracheal bronchitis reached 83.9%,the difference being statistically significant(P<0.01).Among the 298 cases,the total utilization rate of antibacterial drugs was 85.2%,that of oral antibacterial drugs was 62.2%,and that of injection antibacterial drugs was 50.8%.The common antibiotics prescribed were cephalosporins(63.4%),penicillins(41.3%),macrolides(31.8%),and others(7.0%),etc.About 61.4%of patients were treated with one antibacterial drug alone,30.8%with two combined drugs,7.4%with three combined drugs and 0.3%with four combined drugs,respectively,and the difference was statistically significant(P<0.01).Conclusion The use of antimicrobial agents in children's respiratory diseases in this region is not very reasonable,which is manifested in the deficiency in drug indication,route of administration,variety selection and combination of drugs.It is still very important to raise awareness of antimicrobial resistance,organize education and training,and strengthen the construction and supervision of primary health care.