| 基于贝叶斯网络与决策树的中药注射剂致药品不良反应的流行病学特点研究 |
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| 引用本文： | 黎鹂,覃慧莲,甘键钟,邝俊健,梁健龙,梁杰豪,黄秋燕,梁波,李甜,梁俊.基于贝叶斯网络与决策树的中药注射剂致药品不良反应的流行病学特点研究[J].中国医院用药评价与分析,2021(1):101-104,108. |
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| 作者姓名： | 黎鹂 覃慧莲 甘键钟 邝俊健 梁健龙 梁杰豪 黄秋燕 梁波 李甜 梁俊 |
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| 作者单位： | 梧州市中医医院药学部;梧州市中医医院外三科;梧州市中医医院下肢骨二科;梧州市药事管理质量控制中心 |
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| 基金项目： | 广西壮族自治区中医药局自筹经费科研课题(No.GZZC2019276)。 |
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| 摘 要： | 目的:探讨广西壮族自治区梧州市(以下简称"梧州地区")中药注射剂致药品不良反应(adverse drug reaction,ADR)的流行病学特点.方法:收集2011—2019年梧州地区中药注射剂致ADR报告,使用Microsoft ACCESS软件构建数据库,进而以SPSS Modeler 14.1数据挖掘平台,应用...
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| 关 键 词： | 中药注射剂 数据挖掘 药品不良反应 决策树 贝叶斯网络 |
Epidemiological Characteristics of Adverse Drug Reactions Induced by Traditional Chinese Medicine Injections Based on Bayesian Network and Decision Tree |
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| LI Li,QIN Huilian,GAN Jianzhong,KUANG Junjian,LIANG JianLong,LIANG Jiehao,HUANG Qiuyan,LIANG Bo,LI Tian,LIANG Jun.Epidemiological Characteristics of Adverse Drug Reactions Induced by Traditional Chinese Medicine Injections Based on Bayesian Network and Decision Tree[J].Evaluation and Analysis of Drug-Use in Hospital of China,2021(1):101-104,108. |
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| Authors: | LI Li QIN Huilian GAN Jianzhong KUANG Junjian LIANG JianLong LIANG Jiehao HUANG Qiuyan LIANG Bo LI Tian LIANG Jun |
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| Institution: | (Dept.of Pharmacy,Wuzhou Hospital of Traditional Chinese Medicine,Guangxi Wuzhou 543002,China;Dept.of Surgery,Wuzhou Hospital of Traditional Chinese Medicine,Guangxi Wuzhou 543002,China;Dept.of Orthopedics,Wuzhou Hospital of Traditional Chinese Medicine,Guangxi Wuzhou 543002,China;Wuzhou Pharmaceutical Administration Quality Control Center,Guangxi Wuzhou 543002,China) |
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| Abstract: | OBJECTIVE:To probe into the epidemiological characteristics of adverse drug reactions(ADR)induced by traditional Chinese medicine injections in Wuzhou,Guangxi Zhuang Autonomous Region(Hereinafter referred to as"Wuzhou").METHODS:ADR reports induced by traditional Chinese medicine injections in Wuzhou from 2011 to 2019 were collected.Microsoft ACCESS software was used to establish the database,and SPSS Modeler14.1 data mining platform was used to carry out data mining research based on CART,CHAID decision tree algorithm and Bayesian network methods.RESULTS:A total of 1370 detailed cases of ADR induced by traditional Chinese medicine injections were collected,of which 1239 cases were general(90.44%)and 131 cases were severe(9.56%).The results of Bayesian network analysis showed that the clinical manifestations of ADR induced by traditional Chinese medicine injection were related to the age of patients.In the age group of>60 years old,the proportion of skin damage gradually decreased,and the proportion of other system damage gradually increased.The results of cart algorithm showed that the main clinical manifestation of ADR was skin damage,and skin damage was the main manifestation of ADR in all age groups.The results of decision tree CHAID algorithm show that the main clinical manifestation of ADR was skin damage,the general ADR was mainly skin damage,and the serious ADR were mainly systemic damage and respiratory damage..CONCLUSIONS:The epidemiological characteristics of ADR induced by traditional Chinese medicine injections in Wuzhou may be related to the age of patients,occurrence time of ADR and types of ADR,which need to be analyzed and verified by data analysis of a larger sample size. |
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| Keywords: | Traditional Chinese medicine injections Data mining Adverse drug reactions Decision tree Bayesian network |
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