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| 褐藻小粘膜藻中的溴酚化合物 | |
| 引用本文： | 徐秀丽,范晓,宋福行,石建功. 褐藻小粘膜藻中的溴酚化合物[J]. 中国中药杂志, 2005, 30(1): 39-41 |
| 作者姓名： | 徐秀丽 范晓 宋福行 石建功 |
| 作者单位： | 1. 中国科学院,海洋研究所,山东,青岛,266071;中国科学院,研究生院,北京,100039 2. 中国科学院,海洋研究所,山东,青岛,266071 3. 中国医学科学院,中国协和医科大学,药物研究所,北京,100050 |
| 基金项目： | 国家自然科学基金，国家高技术研究发展计划(863计划) |
| 摘 要： | 目的 :对褐藻小粘膜藻进行化学成分研究。方法 :利用正相硅胶柱色谱 ,SephadexLH 2 0柱色谱、反相HPLC及重结晶等分离手段和IR ,MS及NMR等结构鉴定方法。结果 :从小粘膜藻中分离鉴定了 6个溴酚类化合物 ,分别为 2 ,2′ ,3,3′ 四溴 4 ,4′,5 ,5′ 四羟基二苯甲烷 (1) ,2 ,2′,3 三溴 3′ ,4 ,4′ ,5 四羟基 6′ 乙氧甲基二苯甲烷 (2 ) ,2 ,3 二溴 4 ,5 二羟基苯甲醇 (3) ,2 ,3 二溴 4 ,5 二羟基苯甲基甲醚 (4) ,3 溴 4 羟基苯甲酸 (5 )及 2 溴 4 ,5 二羟基苯甲醛 (6 )。结论 :这些化合物均为首次从该属海藻中发现。 |
| 关 键 词： | 褐藻 小粘膜藻 化学成分 结构鉴定 溴酚 |
| 文章编号： | 1001-5302(2005)01-0039-03 |
| 收稿时间： | 2003-10-10 |
Bromophenols from the brown alga Leathesia nana |
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| XU Xiu-li;FAN Xiao;SONG Fu-hang;SHI Jian-gong. Bromophenols from the brown alga Leathesia nana[J]. China Journal of Chinese Materia Medica, 2005, 30(1): 39-41 | |
| Authors: | XU Xiu-li FAN Xiao SONG Fu-hang SHI Jian-gong |
| Affiliation: | Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China. |
| Abstract: | OBJECTIVE: To investigate the chemical constituents of the brown alga Leathesia nana. METHOD: Compounds were isolated by normal phase silica gel, Sephadex LH-20 chromatography and reverse phase HPLC techniques. Their structures were elucidated with spectroscopic methods including IR, MS and NMR. RESULT: Six compounds were isolated from ethanolic extract of the brown alga L. nana and their structures were identified as 2,2',3,3'-tetrabromo-4,4',5,5'-tetrahydroxydiphenyl methane, 2,2',3-tribromo-3', 4,4', 5-tetrahydroxy-6'-ethyloxymethyldiphenyl methane, 2,3-dibromo-4,5-dihydroxybenzyl alcohol, 2,3-dibromo-4,5-dihydroxybenzyl methyl ether, 3-bromo-4-hydroxybenzoic acid and 2-bromo-4,5-dihydroxybenzaldehyde. CONCLUSION: All these compounds were obtained from this species for the first time. |
| Keywords: | brown alga Leathesia nana chemical constituent structure elucidation bromophenol |
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