| 电离辐射对内皮细胞和淋巴细胞粘附特性的影响 |
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| 引用本文： | 张作明,郭鹞,杜红俊,郭守一,骆阁大. 电离辐射对内皮细胞和淋巴细胞粘附特性的影响[J]. 微循环学杂志, 1998, 8(4): 9-11 |
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| 作者姓名： | 张作明 郭鹞 杜红俊 郭守一 骆阁大 |
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| 作者单位： | 1. 中国人民解放军第四军医大学航空临床医学教研室,西安710032
2. 中国人民解放军第四军医大学放射医学教研室,西安710032 |
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| 摘 要： | 从电离辐射对微血管内皮细胞和淋巴细胞粘附力影响的角度进一步探讨辐射致微循环损伤的机制。方法：采用细胞粘附观察记录装置，观察不同剂量电离辐射作用对培养的内皮细胞和外周血淋巴细胞粘附特性的影响。结果：不同剂量γ射线（60Co）辐射作用内皮细胞（10、15Gy）或淋巴细胞（3、5Gy）后，二者的粘附特性分别发生了明显的改变，表现为二种细胞间的粘附数量明显增多。结论：电离辐射作用下微循环的损伤性变化可能与内皮细胞和淋巴细胞的粘附特性改变有关。
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| 关 键 词： | 电离辐射 微血管 内皮细胞 淋巴细胞 粘附 兔 |
Effects of Ionizing Radiation on Adhesion Characteristic of Microvascular Endothelial Cells and Lymphocyte |
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| Zhang Zuoming, Guo Yao, Du Hongjun,et al. Effects of Ionizing Radiation on Adhesion Characteristic of Microvascular Endothelial Cells and Lymphocyte[J]. Chinese Journal of Microcirculation, 1998, 8(4): 9-11 |
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| Authors: | Zhang Zuoming Guo Yao Du Hongjun et al |
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| Abstract: | Objective: To further investigate the effects of ionizing radiation on micro circulation. Method: Quantified adhesion of Peripheral blood lymphocyte to cul tured rabbits brain microvascular endothelial cells after γ (6oCo) irradiation with a parallel-palate flow chamber under inverted microscope. Result: after γ irradiation on brain microvascular endothelial cells(10, 15 Gy) or peripheral blood lymphocyte(3, 5 Gy), the adhesion of lymphocyte to microvascular en dothelial cells was increased significantly. Conclusion: the result suggests that the mechanism of irradiation injures on microcirculation may be related to the ad hesion characteristic change of lymphocyte and microvascular endothelial cells. |
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| Keywords: | Ionizing radiation Microvascular Endothelial cell Lymphocyte Adhesion Rabbit |
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