腹腔镜下卵巢子宫内膜异位症保守性手术后应用左炔诺孕酮宫内缓释系统的临床疗效

目的探讨腹腔镜下卵巢子宫内膜异位症保守性手术后应用左炔诺孕酮官内缓释系统(LNG-IUS)的临床疗效。方法对行腹腔镜保守性手术的卵巢子宫内膜异位症患者150例,术后放置LNG-IUS,观察其临床疗效和副反应。结果术后LNG-IUS放置前和放置后3个月、6个月和12个月,月经量和痛经VAS评分逐渐下降,子宫内膜厚度逐渐变薄,差异均具有显著性;放置后3个月,患者月经期较放置前明显延长,之后逐渐缩短,差异有统计学意义。随访12个月,累计复发率为14.7%。副反应以月经间期出血为主。结论 LNG-IUS可以改善腹腔镜下卵巢子宫内膜异位症保守性手术后的症状和体征,是一种有效、副反应小,依从性高的治疗方法,并在一定程度上预防术后内异症的复发,

Effect of Levonorgestrel Releasing Intrauterine Device Placed in Ovarian Endometriosis After Laparoscopic Operations

Objective To discuss the effect of levonorgestrel releasing intrauterine device（LNG-IUD） placed in ovarian endometriosis after laparoscopic operations. Methods By observing the curative effect and adverse effect on 150 LNG-IUD placed in 76 after laparoscopie operations cases of ovarian endometriosis. Results The endometrium before the place of LNG-IUS was significantly thinner, the menstrual blood volume and dysmenorrhea VAS score before the place of LNG-IUS were shortened obviously than those in 3,6,12 months after the place of LNG-IUS. The menstrual period in 3 months after the place of LNG-IUS was significantly longer than that before the place of LNG-IUS. The menstrual period in 3, 6, 12 months after the place of LNG-IUS were shortened obviously than that before the place of LNG-IUS. The rate of recurrence during 12 months follow-up was 14.7%.Iregular bleeding is the main side effects. Conclusions LNG-IUS placed in ovarian endometriosis after laparoscopic operations can reduce symptoms and signs,and delays disease recurence.