复方南星止痛膏治疗痛痹型膝关节骨性关节炎临床观察

目的:观察复方南星止痛膏治疗痛痹型膝关节骨性关节炎的临床疗效。方法:将80例痛痹型膝关节骨性关节炎患者随机分为治疗组、对照组各40例,治疗组采用复方南星止痛膏加抗骨增生胶囊治疗,对照组采用狗皮膏加抗骨增生胶囊治疗。观察临床疗效、Lysholm膝关节评分量表、疼痛视觉模拟评分(VAS)等情况。结果:治疗组治愈31例,显效6例,好转2例,无效1例,愈显率为92.5%。对照组治愈22例,显效7例,好转6例,无效5例,愈显率为72.5%。2组愈显率比较,差异有显著性意义(P<0.05)。2组治疗后Lysholm膝关节评分升高,与治疗前比较,差异均有显著性意义(P<0.05);2组组间治疗后比较,差异也有显著性意义(P<0.05)。2组治疗后VAS降低,与治疗前比较,差异均有显著性意义(P<0.05);2组组间治疗后比较,差异也有显著性意义(P<0.05)。结论:复方南星止痛膏治疗痛痹型膝关节骨性关节炎疗效显著,值得临床推广。

Clinical Efficacy of Compound Nanxing Zhitong Ointment on Agonizing-arthragia Type Knee Osteoarthritis

Objective:To observe the clinical efficacy of Compound Nanxing Zhitong Ointment on agonizing-arthragia type knee osteoarthritis(KOA).Methods:Eighty patients with agonizing-arthragia type KOA were equally randomized into two groups.The treatment group was treated with Compound Nanxing Zhitong Ointment and Anti-hyperostosis Capsules,and the control group was given Goupi Ointment and Anti-hyperostosis Capsules.The therapeutic effect was evaluated by the scores of Lysholm knee rating scale and pain visual analog scale.Results: In the treatment group,31 patients were cured,6 markedly effective,2 improved,one ineffective,and the markedly effective rate was 92.5%.In the control group,22 were cured,7 markedly effective,6 improved,5 ineffective,and the markedly effective rate was 72.5%.The difference of the markedly effective rate was significant between two groups(P<0.05).After treatment,the Lysholm knee scores of two group were significantly increased and VAS scores were significantly decreased compared with those before treatment(P < 0.05),and the differences were significant between the two groups(P < 0.05).Conclusion:The effect Compound Nanxing Zhitong Ointment is extraordinary for the treatment of agonizing-arthragia type knee osteoarthritis,which is expected to be used in clinic extensively.