舒肝解郁胶囊治疗广泛性焦虑障碍临床观察

目的:观察舒肝解郁胶囊治疗广泛性焦虑障碍的临床疗效。方法:将80例患者随机分成2组,治疗组40例以舒肝解郁胶囊治疗,对照组40例以度洛西汀片治疗。疗程为6周。采用汉密尔顿焦虑量表(HAMA)评定疗效,用症状量表(TESS)评定用药不良反应。结果:治疗组治愈率12.5%,有效率80.0%;对照组治愈率15.0%,有效率82.5%。2组治愈率和有效率比较,差异均无显著性意义(P>0.05)。2组治疗后HAMA评分均逐渐减低,治疗1、2、4、6周后均较治疗前显著下降,差异均有非常显著性意义(P<0.01)。治疗6周后2组间HAMA评分比较,差异无显著性意义(P>0.05)。2组不良反应比较,差异无显著性意义(P>0.05)。结论:舒肝解郁胶囊治疗广泛性焦虑障碍疗效确切,安全性好。

Clinical Study of Sugan Jieyu Capsules in Treatment of Generalized Anxiety Disorder

Objective:To explore the clinical efficacy of Sugan Jieyu capsules in the treatment of generalized anxiety disorder.Methods:Eighty patients with generalized anxiety disorder were equally randomized into two groups.The treatment group received Sugan Jieyu capsules and the control group received Duloxetine Tablets.The treatment course covered six weeks.The clinical effect was assessed by Hamilton anxiety scale(HAMA),and adverse reaction was assessed by treatment emergent symptom scale(TESS).Results:The cure rate was 12.5% and the total effective rate was 80.0% in the treatment group,and was 15% and 82.5% respectively in the control group,the differences being insignificant(P > 0.05).During the treatment,the scores of HAMA were gradually decreased in both groups,and the differences were significant at the end of treatment(P < 0.05compared with those before treatment).The differences of HAMA scores between the two groups after treatment was insignificant(P > 0.05),and the incidence of adverse reactions between the two groups was also insignificant(P > 0.05).Conclusion:Sugan Jieyu capsules are effective and safe for the treatment of generalized anxiety disorder.