克糖宁胶囊治疗2型糖尿病临床疗效观察

目的　观察克糖宁胶囊治疗 2型糖尿病的临床疗效。方法　 3 0 0例 2型糖尿病患者随机分为2组。治疗组 2 2 0例口服自拟克糖宁胶囊 ,每次 2～ 4粒 ,每日 3次 ;对照组 80例口服参芪降糖颗粒 ,每次 3g,每日 3次。 2组均 4周为 1个疗程 ,治疗前及治疗 2周时分别检测空腹及餐后 2h血糖 ,并观察 2组临床疗效和临床主要症状改善情况。结果　治疗组临床总有效率为 97.72 % ,对照组为 76.2 5 % ,2组比较有显著性差异 (P <0 .0 5 ) ;2组治疗后空腹血糖、餐后 2h血糖、总胆固醇、甘油三酯均有降低 ,但治疗组变化较对照组明显 (P <0 .0 5 ) ,高密度脂蛋白胆固醇轻度升高 ,但 2组比较无显著性差异 (P >0 .0 5 ) ;治疗组治疗后主要症状较对照组有明显改善 (P <0 .0 5 )。结论　克糖宁治疗 2型糖尿病可明显改善患者临床症状 ,降低血糖、血脂水平 ,疗效确切。

Observation of type 2 diabetes mellitus treated by Ketangning capsule

Objective To observe the effect of type 2 diabetes mellitus treated by Ketangning capsule. Methods 300 cases with type 2 diabetes mellitus were randomly divided into treatment and control groups. Patients in treatment group (n=220) were treated by Ketangning capsule, 2-4 tablets once, 3 times a day. Patients in control group (n=80) were treated by Shenqijiangtang granules, 3g once, 3 times a day, with a course of 4 weeks in both groups. Improvement of symptoms, fasting glucose and postprandial glucose were observed before and after treatment. Results The total effective rate in treatment group (97.72%) was higher than that in control group (76.25%, P<0.05). Improvement of symptoms, fasting glucose, postprandial glucose, total Cholesterol and triglyceride in treatment group were superior to those in control group (P<0.05). Conclusion Ketangning capsule is effective in treatment of type 2 diabetes mellitus, which can improve fasting glucose and postprandial glucose.