OCT和视野检查在慢性闭角型青光眼诊断中的对比观察

目的观察OCT在慢性闭角型青光眼早期诊断中的应用价值。方法选择于郑州大学第一附属医院就诊的慢性闭角型青光眼（包括早期、进展期以及绝对期）患者23例（37眼）及正常人26例（43眼）,分别利用OCT检查其视盘上方、下方、颞侧、鼻侧及全周平均RNFL厚度和平均视野缺损（MD）,比较其之间的统计学差异及相关性。结果正常组的上方、下方、颞侧、鼻侧四象限及平均RNFL厚度及平均视野缺损（MD）与慢性闭角型青光眼早期、进展期、绝对期比较差异具有统计学意义（P〈0.05）。两种测量方法间比较无统计学意义（P〉0.05）。慢性闭角型青光眼各期的全周平均RNFL厚度与视野MD参数之间均呈现负相关（P〈0.05）。结论OCT检测RNFL厚度结果结合视野检查,在慢性闭角型青光眼的诊断和病情预测中有较好的临床应用价值。

Comparison of tests between OCT and visual field examination in diagnosis of chronic angle- closure glaucoma

Objective To explore the application value of OCT in the early diagnosis of chronic close- angle glaucoma（CPACG）. Methods Statistical difference and correlation between the thickness of RNFL,including of the optic disc above and below,temporal,nasal and full week average thickness and average thickness of RNFL,and the mean deviation（MD） of 23 patients of CPACG（37 eyes）（ including early,progression,andthe absolute phase） and 26 normal controls（43 eyes） at our hospital was studied by us using OCT. Results ①The thickness of RNFL,including of the optic disc above and below,temporal,nasal and full week average thickness and average thickness of RNFL,and the mean deviation（MD） of the experimental group and the control group is with statistically significant difference（〈 P 0. 05）.The entire circumference of each period the average RNFL thickness and visual field MD of CPACG show negative correlation between the parameters（P〈 0. 05）. ②MD is a statistically significant difference（P〈 0. 05） between the experimental group and the control group. Between the groups of CPACG,the MD also has a statistically significant difference（P 〈0.05）. ③The entire circumference of the normal group,the average RNFL thickness and visual field MD parameters no significant correlation（P〉 0. 05）. Comparison of tests between OCT and visual field has no statistical significance（P〉 0. 05）. The entire circumference of each period the average RNFL thickness and visual field MD of CPACG showed a negative correlation between the parameters（ P〈 0. 05）. Conclusion Because of the good reproducibility,OCT can detect the RNFL thickness of glaucoma reliable and effective follow up in line. OCT in the follow- up of suspected glaucoma population to dynamically detect subtle changes in vision compared to more objective. OCT is conducive to chronic angle- closure glaucoma glaucoma early diagnosis,early treatment,and is conducive to individual target IOP glaucoma surgery to determine.