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| 五拗汤及其组方药材挥发油GC-MS比较分析 | |
| 引用本文： | 周玲,唐于平,吴德康,范欣生,丁安伟.五拗汤及其组方药材挥发油GC-MS比较分析[J].中国中药杂志,2009,34(10):1245. |
| 作者姓名： | 周玲 唐于平 吴德康 范欣生 丁安伟 |
| 作者单位： | 南京中医药大学江苏省方剂研究重点实验室,江苏,南京,210046 |
| 基金项目： | 国家“十一五”科技支撑计划项目(2006BAI06A02-01)；江苏省高校“青蓝工程”科技创新团队培养对象项目(2006年度) |
| 摘 要： | 目的:探讨五拗汤各组方药材组成复方后挥发油的组成成分变化.方法:采用水蒸气蒸馏法提取五拗汤及其富含挥发油的组方药材麻黄、苦杏仁、桔梗和荆芥的挥发油,并通过GC-MS联用技术对其进行分析鉴定和比较研究.结果:五拗汤挥发油的GC-MS TIC化学信号主要来源于组方药材麻黄、桔梗、荆芥的贡献,但是也发现单味药材中一些化学信号在复方五拗汤中未检测到.结论:利用GC-MS比较分析方法研究五拗汤各组方药材组成复方后挥发性成分的变化,为揭示其效应物质基础和配伍机理奠定基础. |
| 关 键 词： | 五拗汤 挥发油 GC-MS |
Comparative analysis of volatile oils of Wuao decoction and its major constituing herbs by GC-MS |
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| ZHOU Ling,Tang-Xu-Beng-,Tun-De-Kang,Fan-Xin-Sheng-,Ding-An-Wei.Comparative analysis of volatile oils of Wuao decoction and its major constituing herbs by GC-MS[J].China Journal of Chinese Materia Medica,2009,34(10):1245. | |
| Authors: | ZHOU Ling Tang-Xu-Beng- Tun-De-Kang Fan-Xin-Sheng- Ding-An-Wei |
| Institution: | Jiangsu Key Laboratory for Traditional Chinese Medicine Formulae Research, Nanjing University of Chinese Medicine, Nanjing 210046, China |
| Abstract: | Objective: To evaluate the correlativity between volatile components of Wuao decoction and its major constituting herbs. Method: The chemical compositions of essential oil, obtained by hydrodistillation from Wu-ao Decoction and its major constituting herbs (Herba Ephedrae, Semen Armeniacae Amarum, Radix Platycodi,Herba Schizonepetae), were analyzed by GC-MS. Result: The volatile components of Wu-ao Decoction were mostly derived from Herba Ephedrae, Radix Platycodi and Herba Schizonepetae. Conclusion: The method of GC-MS can be used to investigate the volatile component changes in traditional Chinese medicine formulae. |
| Keywords: | Wuao decoction volatile oil GC-MS |
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