| 左氧氟沙星和呋喃唑酮根除幽门螺杆菌感染的疗效观察 |
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| 引用本文： | 丛春莉,苏秉忠. 左氧氟沙星和呋喃唑酮根除幽门螺杆菌感染的疗效观察[J]. 内蒙古医学院学报, 2009, 31(2) |
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| 作者姓名： | 丛春莉 苏秉忠 |
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| 作者单位： | 内蒙古医学院附属医院,消化内科,内蒙古,呼和浩特,010050 |
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| 基金项目： | 内蒙古自治区卫生厅Ⅰ类 |
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| 摘 要： | 目的：比较含左氧氟沙星、呋喃唑酮的四联和三联疗法根除幽门螺杆菌（Hp）感染的疗效、安全性。方法：选择97例符合条件的Hp阳性的慢性胃炎和消化性溃疡的病人,随机分成两组,四联组采用奥美拉唑20mg、胶体果胶铋200mg、左氧氟沙星200mg、呋喃唑酮200mg,bid,口服10d;三联组除没有胶体果胶铋外,余项同。治疗结束4wk后,复查^14C-尿素呼吸试验,观察Hp根除情况、症状及不良反应等。结果：根据意向处理分析（ITT）和试验方案分析（PP）,四联组的Hp根除率分别为90.00%、91.83%,三联组的Hp根除率分别为74.00%、77.08%;四联组根除率较三联组明显高,差异有统计学意义（P〈0.05）。四联组药物不良反应发生率为10.20%,三联组为10.42%,差异没有统计学意义（P〉0.05）。结论：四联疗法Hp根除率高,是根除Hp的理想方案,可作为我区一线治疗选择。
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| 关 键 词： | 幽门螺杆菌 左氧氟沙星 呋喃唑酮 |
THE CLINICAL OBSERVATION FOR ERADICATION OF HELICOBACTER PYLORI INFECTION WITH FURAZOLIDONE AND LEVOFLOXACIN |
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| CONG Chun-li,SU Bing-zhong. THE CLINICAL OBSERVATION FOR ERADICATION OF HELICOBACTER PYLORI INFECTION WITH FURAZOLIDONE AND LEVOFLOXACIN[J]. Acta Academiae Medicinae Neimongol, 2009, 31(2) |
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| Authors: | CONG Chun-li SU Bing-zhong |
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| Affiliation: | CONG Chun-li,SU Bing-zhong(Department of Digestive,Affiliated Hospital,Inner Mongolia Medical College,Hohhot 010050 China) |
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| Abstract: | Objective:To study the efficacy and safety of quadruple versus triple therapy with furazolidone and levofloxacin for eradication of Helicobacter pylori(Hp)infection.Methods:97 cases with Hp infection suffering from chronic gastritis and peptic ulcer were randomized to quadruple therapy group and triple therapy group.The quadruple therapy group was administered omeprazole(20mg),colloidal bismuth pectin(200mg),levofloxacin(200mg),furazolidone(200mg),bis in die for 10 days;while triple therapy group was the sa... |
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| Keywords: | Helicobacter pylori levofloxacin furazolidone |
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