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毛叶香茶菜二萜成分研究
引用本文:董艳臣,高革,张积霞,韩全斌,孙汉董.毛叶香茶菜二萜成分研究[J].新乡医学院学报,2003,20(4):247-248,251.
作者姓名:董艳臣  高革  张积霞  韩全斌  孙汉董
作者单位:1. 新乡医学院,河南,新乡,453003
2. 中国科学院昆明植物研究所植物化学开放实验室,云南,昆明,650204
摘    要:目的 进一步研究毛叶香茶菜的化学成分及生物活性。方法 利用反复硅胶柱层析进行分离和纯化 ,通过各种波谱分析鉴定其结构。结果 从毛叶香茶菜的 70 %丙酮粗提物的乙酸乙酯部分得到 5个已知的对映—贝壳杉烷型二萜 ,分别为Epinodosin(Ⅰ )、Odonicin(Ⅱ )、Lasiodonin(Ⅲ )、冬凌草甲素 (OridoninⅣ )、Shikokianin(Ⅴ )。结论 化合物Lasiodonin(Ⅲ )为首次从该植物中分得

关 键 词:毛叶香茶菜  对映—贝壳杉烷型二萜  波谱分析
文章编号:1004-7239(2003)04-0247-03

Study on chemical component of diterpenoids of Isodon Japonica
DONG Yan-chen ,GAO Ge ,ZHANG Ji-xia ,HAN Quan-bin ,SUN Han-dong.Study on chemical component of diterpenoids of Isodon Japonica[J].Journal of Xinxiang Medical College,2003,20(4):247-248,251.
Authors:DONG Yan-chen  GAO Ge  ZHANG Ji-xia  HAN Quan-bin  SUN Han-dong
Institution:DONG Yan-chen 1,GAO Ge 1,ZHANG Ji-xia 1,HAN Quan-bin 2,SUN Han-dong 2
Abstract:Objective To reseach the constituent and bioactivity of Isodon Japonica.Methods The compounds were isolated and purified repeatedly by Si?gel column chromatography, and their structures were determined as Epinodosin(Ⅰ), Odonicin(Ⅱ), Lasiodonin(Ⅲ), Oridonin (Ⅳ) and Shikokianin(Ⅴ) by spectroscopic methods respectively.Results Five known ent-kaurance diterpenoids compounds were obtained from the EtOAc fraction of the 70% acetone extract.Conclusion Compounds Lasiodonin(Ⅲ) was isolated from this plant for the first time.
Keywords:Isodon Japonica  ent-kaurance  diterpenoids  chromatography
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