膀胱混合癌的诊断和治疗

 目的　提高膀胱混合癌的诊治水平。方法　回顾分析 1 990年 1月至 2 0 0 0年 6月收治的 1 2例病人 ,结合文献就其临床表现、诊断和治疗以及预后情况进行讨论。结果　 1 2例膀胱混合癌占同期 5 49例膀胱肿瘤的 2 .1 9% ,其中鳞、腺混合癌 3例 ,移行、鳞状、腺细胞混合癌 1例 ,移行、鳞状细胞混合癌 6例 ,移行、腺细胞癌混合癌 2例。行膀胱部分切除术 9例 ,全膀胱切除 2例 ,根治性全膀胱切除 1例。术后 1 2例患者均接受定期随访 ,生存期 7个月～ 4.2年。结论　膀胱混合癌的恶性程度高 ,预后极差 ,手术切除仍是主要的治疗方法 ,早期诊断是提高生存率的关键

The diagnosis and treatment of the bladder mixed tumor

Objective To improve the diagnosis and treatment of the bladder mixed tumor.Methods 12 cases treated from Jan.1990 to June.2000 were reviewed. The clinical manifestations,diagnosis, treatment and prognosis were discussed.Results 12 cases of the bladder mixed tumor accounted for 2.19% of 549 bladder tumor patients in the same period, of which 3 of 12 were squamous| adenocarcinoma mixed tumor, 1 transitional|squamous|adenocarcinoma, 6 transitional|squmous and 2 transitional|adenocarcinoma. Partial cystectomy were undergone for 9 of 12 cases, total cystectomy for 2 and radical total cystectomy for 1.The survival time was 7 months to 4.2 years.Conclusion There were higher malignancy and worse prognosis in bladder mixed tumor. Radical total cystectomy seems to be the best method of reatment. Early diagnosis might prolong survival.