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| 白细胞介素在扩张型心肌病患者血清中的表达及意义 | |
| 引用本文： | 李秀玉,辛晓敏,刘凤岐.白细胞介素在扩张型心肌病患者血清中的表达及意义[J].中国实验诊断学,2009,13(8):1035-1037. |
| 作者姓名： | 李秀玉 辛晓敏 刘凤岐 |
| 作者单位： | 1. 首都医科大学宣武医院,检验科,北京,100053 2. 哈尔滨医科大学第一临床医学院,检验科,黑龙江,哈尔滨,150001 3. 哈尔滨医科大学第一临床医学院,心内科,黑龙江,哈尔滨,150001 |
| 基金项目： | 黑龙江省"十五"科技攻关项目 |
| 摘 要： | 目的观察扩张型心肌病（DCM）患者血清中的白细胞介素6（IL-6）,白细胞介素1α（IL-1α）,可溶性白细胞介素-2受体（SIL-2R）及白细胞介素10（IL-10）的水平,探讨其意义。方法扩张型心肌病患者组35例,健康对照组21例,用ELISA方法测定IL-6,IL-1α,SIL-2R,IL-10水平,并对其结果进行比较。结果DCM患者血清中IL-6,IL-1α,SIL-2R及IL-10水平明显高于健康对照组（P〈0.05）。结论DCM患者血清中IL-6,IL-1α,sIL-2R及IL-10水平的升高,说明DCM的发生、发展与免疫因素重要相关。 |
| 关 键 词： | 扩张型心肌病 IL-6 IL-1α SIL-2R IL-10 |
Detection and evaluation of the serum interleukins in patients with DCM |
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| LI Xiu-yu,XIN Xiao-min,LIU Feng-qi.Detection and evaluation of the serum interleukins in patients with DCM[J].Chinese Journal of Laboratory Diagnosis,2009,13(8):1035-1037. | |
| Authors: | LI Xiu-yu XIN Xiao-min LIU Feng-qi |
| Institution: | LIXiu-yu,XINXiao-min, LIUFeng-qi(1. Department of Laboratory Diagnosis,XuanWu Hospital of the Capital University of Medical Sciences, Beijing 100053, China; 2. Department of Laboratory Diagnosis, The First Clinical College, Harbin Medical University, Harbin 150001, China ; 3. Department of Cardiology, The First Cliniccd College, Harbin Medical University , Harbin 150001, China) |
| Abstract: | Objective To observe the concentrations of the serum IL-6、IL-1α,SIL-2R and IL-10 in patients with DCM.Methods The concentrations of the serum IL-6 、IL-1α、SIL-2R and IL-10 were assayed by ELISA in 35 patients with DCM and we compared it with those of 21 age matched healthy control subjects.Results The concentrations of the serum IL-6、IL-1α,SIL-2R and IL-10 were significantly higher in patients with DCM than those in controls（P＆lt;0.05）.Conclusion The concentrations of the cytokines may suggest that DCM is closely correlated with the immune systerm. |
| Keywords: | IL-6 SIL-2R IL-10 |
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