Glucose-6-Phosphate Dehydrogenase Deficiency in a Native Danish Family A New Variant

Deficiency of red cell glucose-6-phosphate dehydrogenase was found in a native Danish family, in which 2 boys suffered from severe haemolytic anaemia. The mother and 3 sisters of the boys were heterozygotes for G-6-PD deficiency. The biochemical investigations indicate that this deficient G-6-PD is very similar to the Mediterranean variant; however, this variant gene may represent another example of G-6-PD ‘Helsinki’ or an unique variant with properties similar to G-6-PD B(—).