中西医结合治疗中晚期食管癌患者疼痛并焦虑的疗效观察

目的探索中西医结合治疗对中晚期食管癌患者疼痛并焦虑的临床疗效。方法选取2017年1月—2019年1月在河北省民政总医院肿瘤内科住院的中晚期食管癌疼痛并焦虑的患者共92例,随机分为对照组和治疗组,每组各46例,两组患者均给予支持治疗,针对食管癌的抗癌治疗及常规护理,对照组根据疼痛情况按阶梯镇痛治疗,抗焦虑选用盐酸帕罗西汀片,治疗组在对照组基础上给予中西医结合治疗4周,采用疼痛程度数字评估量表(NRS),焦虑自评量表(SAS),评价其疼痛和焦虑改善情况。结果两组患者治疗后NRS和SAS评分均低于治疗前,差异有统计学意义(P<0.05),且治疗组患者NRS和SAS评分低于对照组,差异有统计学意义(P<0.05);治疗组患者疼痛缓解总有效率为73.91%,明显高于对照组疼痛缓解总有效率的45.65%,差异有统计学意义(P<0.05)。结论中西医结合治疗能明显改善中晚期食管癌患者的疼痛和焦虑症状,值得临床推广应用。

Effect of integrated traditional Chinese and western medicine on the treatment of pain and anxiety in patients with advanced esophageal cancer

Objective To explore the clinical efficacy of integrated traditional Chinese and western medicine in treating pain and anxiety in patients with advanced esophageal cancer.Methods A total of 92 patients with advanced esophageal cancer with pain and anxiety admitted to the Hebei Civial Affiars Hospital from January,2017 to January,2019 were included and randomized into the observation group and the control group,with 46 patients in each group.Patients in both groups were given supporting therapy,anticancer therapy and conventional nursing.The control group was additionally given analgesic therapy according to analgesic ladder and given paroxetine hydrochloride for anti-anxiety therapy.The observation group were additionally given integrated traditional Chinese and western medicine treatment for 4 weeks on the basis of the control group.Numeric pain rating scale(NRS)and self-rating anxiety scale(SAS)were used to assess the improvement of pain and anxiety.Results After treatment,NRS and SAS scores in both groups decreased,with statistical significance(P<0.05);and the NRS and SAS scores in the observation group was lower than in the control group,with statistical significance(P<0.05).In terms of total effective rate of pain relief,the observation group(73.91%)was significantly higher than the control group(45.65%),with statistical significance(P<0.05).Conclusion Integrated traditional Chinese and western medicine can effectively relieve pain and anxiety in patients with advanced esophageal cancer,which has high application value.