En bloc kidney transplantation from infant donors younger than 10 months into pediatric recipients |
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| Authors: | Hong‐yang Wang Jun Li Long‐shan Liu Rong‐hai Deng Qian Fu Dicken Shiu‐Chung Ko Huan‐xi Zhang Su‐xiong Deng Chang‐xi Wang |
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| Institution: | 1. Organ Transplantation Center, The First Affiliated Hospital of Sun Yat‐sen University, Guangzhou, China;2. Department of Urology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA;3. Guangdong Provincial Key Laboratory on Organ Donation and Transplant Immunology, Guangzhou, China |
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| Abstract: | Early graft loss and poor graft function limit the use of kidneys from infant donors. Six en bloc kidney transplantations were performed from infant donors younger than 10 months into pediatric recipients between November 2012 and September 2015 at our center. We retrospectively analyzed recipient and donor demographics, surgery procedures, complications, graft function and size, and patient and graft survival with a follow‐up of 6‐39 months (median 15.5 months). Donor age ranged from 1 to 10 months with weight ranging from 3.5 to 10 kg. Recipient age ranged from 10 to 16 years with weight ranging from 30 to 39 kg. One kidney was removed due to arterial thrombosis during surgery, while the other kidney of this en bloc graft remained viable. Urine leak followed by bilateral ureteral obstruction occurred in one recipient. All of the recipients showed immediate graft function. The size of the en bloc kidney increased from 4.2±0.6 cm to 7.6±0.6 cm 6 months after surgery. Patient and graft survival were both 100% at the last follow‐up. Our results show that en bloc kidney transplantation from infant donors younger than 10 months into pediatric recipients is effective under the condition of experienced surgical techniques and perioperative management. |
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| Keywords: | en bloc kidney transplantation infant donors outcome pediatric surgical procedures |
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