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Airway plaque presenting after alteration of immunosuppression in a pediatric patient remote from heart transplantation |
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| Authors: | Thomas D. Ryan Michael J. Absalon Alessandro de Alarcon Anita Gupta Anna L. Peters Angela Lorts Lara A. Danziger‐Isakov Clifford Chin |
| Affiliation: | 1. The Heart Institute, Cincinnati Children's Hospital, Cincinnati, OH, USA;2. Cancer and Blood Diseases Institute, Cincinnati Children's Hospital, Cincinnati, OH, USA;3. Division of Pediatric Otolaryngology, Cincinnati Children's Hospital, Cincinnati, OH, USA;4. Division of Pathology and Laboratory Medicine, Cincinnati Children's Hospital, Cincinnati, OH, USA;5. Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital, Cincinnati, OH, USA;6. Division of Infectious Diseases, Cincinnati Children's Hospital, Cincinnati, OH, USA |
| Abstract: | Success after solid organ transplantation is dependent on the proper balance of immunosuppression to prevent rejection of the allograft while limiting the risk of developing infections and malignancy. We present a 9‐year‐old girl, remote from transplant, who presented with airway plaque after a change in immunosuppression to include the mTOR inhibitor sirolimus. Differential diagnosis included direct medication side effect, infection, and neoplasia. |
| Keywords: | airway EBV heart transplant immunosuppression mTOR inhibitor post‐transplant lymphoproliferative disorder |