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CD56 expression in a case of primary cutaneous CD30+ anaplastic large cell lymphoma
Authors:Chang S E  Park I J  Huh J  Choi J H  Sung K J  Moon K C  Koh J K
Institution:Departments of Dermatology and Pathology, Asan Medical Center, College of Medicine, University of Ulsan, 388-1 Poongnap-Dong, Songpa-Gu, Seoul 138-736, Korea.
Abstract:We describe clinicopathological features of an unusual case of CD30+/CD56+ T-cell lymphoma in a 58-year-old Korean man who presented with disseminated nodules, papules and hyperpigmented patches. Coexpression of CD30 and CD56 in T-cell lymphoma is very rare. Our patient did not respond to an intensive chemotherapy regimen, in contrast to the previously reported cases of primary cutaneous CD30+ anaplastic large cell lymphoma. Coexpression of CD56 might therefore identify a subset of CD30+ lymphomas with more aggressive features.
Keywords:anaplastic large cell lymphoma  CD30  CD56  T-cell lymphoma
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