脑胶质瘤术后放射治疗临床分析

目的: 分析脑胶质瘤术后放射治疗疗效及影响脑胶质瘤患者生存的因素。方法: 对脑胶质瘤低级别39例(Ⅰ+Ⅱ级)、高级别31例(Ⅲ+Ⅳ级)及室管膜瘤4例均进行手术切除,其中肉眼肿块全切31例,大部切除38例,部分切除5例,均在手术后3~4周内接受放射治疗。其中16例高分级患者放射治疗后接受化疗。结果: 年龄<45岁、全切术和病理低级别者1、3和5年生存率较高(P<0.05~P<0.01)。结论: 脑胶质瘤术后放射治疗是有效治疗方法,年龄、病理分级、手术方式、化疗是影响放射治疗脑胶质瘤的重要预后因素。

Radiation therapy for postoperation gliomas

Objective: To evaluate the effect of radiotherapy on gliomas and the prognostic factor.Methods: Seventy-four patients with gliomas were treated by radiotherapy.Among them,39 cases were in low grade(Ⅰ+Ⅱ grade),31 cases in high grade(Ⅲ+Ⅳ grade) and 4 cases had the ependyma tumor.All the patients received radiotherapy in 3-4 weeks after operation.Thirty-one cases were performed total resection,38 cases bulk-resection and 5 cases partial resection.Among them,16 cases of high grade received chemotherapy after radiotherapy.Results: The patients under the age of 45,the total resection group and the patients of lower-ranking in pathology had a higher survival rate(1,3 and 5 years)(P<0.05 to P<0.01).Conclusions: Radiotherapy is effective for patients with gliomas.Age,pathological grading,operation mode are the important prognosis factors.