572例放疗前CT扫描的鼻咽癌患者的生存分析:探讨提高生存率的关键因素

连续抽取中山医科大学肿瘤医院CT室1984年4月至1987年7月所有经病理证实,放射治疗前CT扫描的鼻咽癌572例,以CT显示肿瘤原发灶的准确范围为基础,采用多因素Cox模型,分析各受侵部位对预后的意义,探讨提高鼻咽癌生存率的关键因素。结果表明,正确的T分期是影响生存的最主要因素,其次是N分期。通过对原发病灶15个因素的筛选,按比例危险度的大小列出了主要影响生存的受侵部位。强调加强对颈动脉鞘区的完全控制是提高鼻咽癌生存率的关键因素之一。

A SURVIVAL ANALYSIS OF 572 CASES OF NPC WITH CT-SCAN BEFORE TREATMENT: TO SCREEN THE LEADING PROGNOSTIC FACTORS

572 consecutive cases of histologically proven nasopharyngeal carcinoma(NPC) with CT-scanning before radiothearapy from Apr. 1984 to July 1987 seen at our hospital were analyzed retrospectively. . Basing on the true extent of primary tumor displayed by CT, an attempt was made to screen the leading prognostic factors according to the Cox regression model The results showed that the accurate T-staging, which must refer to CT or MRI, was the most important independent factor influencing the treatment outcome, and the next important factor was N-staging. Among the 15 factors related to the T-staging, the significant factors influencing the survival was presented in the order of proportional hazard. It wes emphasized that the completed control of the disease of carotid sheath area was one of the key factors improving the survival rate of NPC.