| Co-existence of calcitonin gene-related peptide (CGRP) and 5-hydroxytryptamin (5-HT) in rabbit lung |
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| 引用本文： | 张远强. Co-existence of calcitonin gene-related peptide (CGRP) and 5-hydroxytryptamin (5-HT) in rabbit lung[J]. 中国人民解放军军医大学学报, 1993, 0(3) |
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| 作者姓名： | 张远强 |
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| 作者单位： | Department of |
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| 摘 要： | It was investigated that the localization and distribution of calcitonin gene-relatedpeptide (CGRP) in the rabbit lung by ABC-GDN immunohistochemistry.The results demon-strated that CGRP immunoreactivity was located in neuroendocrine cells (NEC_s) and neu-roepthelial bodies (NEB_s),including all airways from bronchi,bronchioles,and alveolar ducts.The nerve fibers in walls of the intrapulmonary bronchi and blood vessels also had CGRP-immunoreactivity.Adjacent sections immunostained with antibodies to CGRP and 5-HT provedthe coexistence of CGRP and 5-HT in NECs and NEBs.This finding suggested the possibilityof functional interaction between the peptide and amine.
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Co-existence of calcitonin gene-related peptide (CGRP) and 5-hydroxytryptamin (5-HT) in rabbit lung |
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| Zhang Yuanqiang. Co-existence of calcitonin gene-related peptide (CGRP) and 5-hydroxytryptamin (5-HT) in rabbit lung[J]. Journal of Medical Colleges of PLA(China), 1993, 0(3) |
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| Authors: | Zhang Yuanqiang |
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| Affiliation: | Zhang Yuanqiang Department of Histology and Embryology,Fourth Military Medical University,Xi'an 710032 |
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| Abstract: | It was investigated that the localization and distribution of calcitonin gene-related peptide (CGRP) in the rabbit lung by ABC-GDN immunohistochemistry.The results demon- strated that CGRP immunoreactivity was located in neuroendocrine cells (NEC_s) and neu- roepthelial bodies (NEB_s),including all airways from bronchi,bronchioles,and alveolar ducts. The nerve fibers in walls of the intrapulmonary bronchi and blood vessels also had CGRP- immunoreactivity.Adjacent sections immunostained with antibodies to CGRP and 5-HT proved the coexistence of CGRP and 5-HT in NECs and NEBs.This finding suggested the possibility of functional interaction between the peptide and amine. |
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| Keywords: | calcitonin gene-related peptide serotonin immunohistochemistry lung rabbits |
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