宫颈及盆腔解脲支原体、沙眼衣原体感染与输卵管性不孕

目的　探讨女性宫颈及盆腔解脲支原体 (UU)和沙眼衣原体 (CT)感染与输卵管性不孕的关系及其感染特点。方法　应用聚合酶链反应 (PCR)法对接受腹腔镜检查的 36例输卵管性不孕患者 (不孕组 )和 2 3例正常生育患者 (对照组 )进行宫颈分泌物和盆腔液体UU、CT检测 ;应用腹腔镜了解输卵管粘连及阻塞程度。结果　两组宫颈分泌物UU阳性率分别为 30 .6 %、8.7% ,两者相比有显著性差异 (P <0 .0 5 ) ;宫颈分泌物CT阳性率两者比较无显著性差异 ;两组盆腔液体UU、CT阳性率相比较无显著性差异 (P >0 .0 5 ) ;不孕组UU阳性患者输卵管周围轻度以下粘连占 5 0 % ,但输卵管阻塞率为 87.5 % ,同组UU阴性患者输卵管周围中、重度粘连占 79.2 % ,输卵管阻塞率为 6 4 .6 % ,两组粘连程度及阻塞率相比均有显著性差异 (P <0 .0 5 )。结论　女性生殖道UU感染与输卵管性不孕相关 ;UU、CT感染症状隐匿 ,但输卵管腔损害明显

TUBAL INFERTILITY AND INFECTIONS OF UREAPLASMA UREALYTICUM AND CHLAMYDIA TRACHOMATIS IN CERVIX AND PELVIS

Objective:To explore the effects of Ureaplasma Urealyticum (UU) and Chlamydia Trachomatis (CT) infections on tubal infertility.Methods:Samples from cervical canal and pelvic fluid of 36 tubal infertile women underwent laparoscopy (study group) and 23 normal fertile women (control group). The polymerase chain reaction (PCR) technique was used for CT-DNA and UU-DNA assays.Results:The UU positive rate of samples from cervical canal infertile group and control group were 30.6% and 8.7% respectively. There was significant difference between the two groups ( P <0.05).No significant difference in CT positive rate between the two groups. UU & CT positive rates of samples from pelvic fluid between the two groups showed no significant difference. The obstructive rate of tubes in UU positive infertile patients was 87.5%, but there was no pelvic adhesion or only mild pelvic adhesion in these patients.Conclusions:UU infection in cervix is a principal pathogenic factor of tubal infertility. Most of patients with genital infection of UU are asymptomatic, but there are severe damages in tubal cavity.