| 红丝线化学成分的研究 |
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| 引用本文： | 杨光忠,赵松,李援朝.红丝线化学成分的研究[J].药学学报,2002,37(6):437-439. |
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| 作者姓名： | 杨光忠 赵松 李援朝 |
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| 作者单位： | 1. 中国科学院上海药物研究所,上海,200031
2. 华东理工大学精细化工研究所,上海,200237 |
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| 摘 要： | 目的研究红丝线(Lycianthes biflora)的化学成分。方法应用各种色谱技术进行分离纯化,用IR,MS,1HNMR,13CNMR和各种2D-NMR技术鉴定化合物的结构,并进行初步的药理实验。结果从红丝线分得5个化合物,分别鉴定为bifloride A (1), N- trans-cinnamoyltyramine (2), liquiritigenin (3), N-trans-p-coumaroyloctopamine (4), 1-O-β-D-glucopyranosyl-2-N-2′-hydroxypalmitoyl-sphinga-4-trans-8-trans-dienine (5)。结论1,2为新化合物,2对P-388白血病细胞有一定抑制作用,其余化合物皆首次从该植物中分得。
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| 关 键 词： | 茄科 红丝线 N- trans-cinnamoyltyramine bifloride A |
| 收稿时间： | 2001-07-10 |
STUDIES ON THE CHEMICAL CONSTITUENTS OF LYCIANTHES BIFLORA |
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| YANG Guang-zhong,ZHAO Song,LI Yuan-chao.STUDIES ON THE CHEMICAL CONSTITUENTS OF LYCIANTHES BIFLORA[J].Acta Pharmaceutica Sinica,2002,37(6):437-439. |
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| Authors: | YANG Guang-zhong ZHAO Song LI Yuan-chao |
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| Affiliation: | Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200031, China. |
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| Abstract: | AIM: To study the chemical constituents of Lycianthes biflora. METHODS: Column chromatography was used to separate the chemical constituents. IR, MS, 1HNMR, 13CNMR and 2D-NMR technique were used to determine the structures of the isolated constituents. RESULTS: Five compounds were isolated from this plant. Their structures were identified to be bifloride A (1), N-trans-cinnamoyltyramine (2), liquiritigenin (3), N-trans-p-coumaroyloctopamine (4), 1-O-beta-D-glucopyranosyl-2-N-2'-hydroxypalmitoyl-sphinga-4- trans-8-trans-dienine (5). CONCLUSION: Compounds 1 and 2 are new compounds, the others were isolated from this plant for the first time. Compound 2 showed inhibitory effects on P-388. |
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| Keywords: | Solanum Lycianthes biflora N trans cinnamoyltyramine bifloride A |
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