| 石见穿多糖SC3的化学研究 |
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| 引用本文： | 刘翠平,王雪松,方积年.石见穿多糖SC3的化学研究[J].药学学报,2002,37(3):189-193. |
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| 作者姓名： | 刘翠平 王雪松 方积年 |
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| 作者单位： | 中国科学院上海生命科学研究院上海药物研究所,上海,200031 |
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| 摘 要： | 目的研究从中药石见穿(Salvia chinensis)全草中得到的酸性多糖SC3的化学结构。方法利用化学方法(糖组成分析、甲基化分析、糖醛酸还原及部分酸水解)和光谱方法(IR,NMR,ESI-MS)分析其结构特征。结果SC3的分子量为7.7×104,由鼠李糖、阿拉伯糖、半乳糖和半乳糖醛酸组成,甲基化分析、部分酸水解和NMR,ESI-MS进一步分析了糖残基的连接方式和序列。结论SC3为一结构复杂的酸性杂多糖,为首次从该植物中分得。
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| 关 键 词： | 石见穿 多糖 结构分析 |
| 收稿时间： | 2001-06-25 |
CHEMICAL STUDIES ON SC3, A POLYSACCHARIDE FROM SALVIA CHINENSIS |
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| LIU Cui-ping,WANG Xue-song,FANG Ji-nian.CHEMICAL STUDIES ON SC3, A POLYSACCHARIDE FROM SALVIA CHINENSIS[J].Acta Pharmaceutica Sinica,2002,37(3):189-193. |
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| Authors: | LIU Cui-ping WANG Xue-song FANG Ji-nian |
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| Institution: | Shanghai Institute of Materia Medica, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China. |
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| Abstract: | AIM: To study the chemical structure of SC3, an acidic polysaccharide from Salvia chinesis. METHODS: Based on chemical (including sugar composition analysis, methylation analysis, uronic acid reduction and partial acid hydrolysis) and spectral analysis (IR, NMR, ESI-MS), the structural characterization of SC3 was investigated. RESULTS: SC3 was composed Rha, Ara, Gal and GalA, with its mean molecular weight of 7.7 x 10(4). By means of methylation analysis, partial acid hydrolysis, NMR and ESI-MS spectrum, the linkages and sequence information of SC3 were obtained. CONCLUSION: SC3 is an complicated acidic polysaccharide, obtained for the first time from the plant. |
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| Keywords: | Salvia chinensis polysaccharides structures analysis |
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