| 黄海葵附生真菌Penicillium thomii的化学成分 |
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| 引用本文： | 蒋亭,田黎,郭爱华,付宏征,裴月湖,林文翰. 黄海葵附生真菌Penicillium thomii的化学成分[J]. 药学学报, 2002, 37(4): 271-274 |
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| 作者姓名： | 蒋亭 田黎 郭爱华 付宏征 裴月湖 林文翰 |
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| 作者单位： | [1]北京大学天然药物及仿生药物国家重点实验室，北京100083 [2]国家海洋局第一海洋研究所生物活性物质重点实验室，山东青岛266003 |
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| 基金项目： | 国家自然科学基金资助项目 ( 40 1760 38，2 9932 0 30 ) . |
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| 摘 要： | 目的研究黄海葵(anemone)附生真菌Penicillium thomii的化学成分。方法用各种色谱技术进行分离纯化,根据理化性质和波谱数据进行结构鉴定。结果从黄海葵附生真菌Penicillium thomii菌丝体中分离得到5个化合物,分别为青霉酮A(I),对甲基苯甲酸(II),1-O-十六碳烷酰-2-O-(9-十八碳烯酰)-3-O-(9,12-十八碳二烯酰)甘油酯(III),5α,8α-环二氧-24ζ-甲基胆甾-6,22-二烯-3β-醇(IV)和大黄素(V)。结论青霉酮A(I)为新化合物,化合物II,III,IV和V系首次从该属中分离得到。
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| 关 键 词： | 真菌 青霉属 青霉酮A |
| 收稿时间： | 2001-09-17 |
CHEMICAL CONSTITUENTS FROM MARINE FUNGUS PENICILLIUM THOMII |
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| JIANG Ting,TIAN Li,GUO Ai-hua,FU Hong-zheng,PEI Yue-hu,LIN Wen-han. CHEMICAL CONSTITUENTS FROM MARINE FUNGUS PENICILLIUM THOMII[J]. Acta pharmaceutica Sinica, 2002, 37(4): 271-274 |
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| Authors: | JIANG Ting TIAN Li GUO Ai-hua FU Hong-zheng PEI Yue-hu LIN Wen-han |
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| Affiliation: | National Research Laboratories of Natural and Biomimetic Drugs, Peking University, Beijing 100083, China. |
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| Abstract: | AIM: To investigate the bioactive constituents from the mycelium of Penicillium thomii. Which isolated from Anemone collected in Qingdao beach. METHODS: The constituents were separated by using various chromatography and the structures were identified on the basis of extensive spectral analysis. RESULTS: Five compounds, namely penicillixanthone A (I), p-methylbenzolic acid (II), 1-O-hexadecanoyl-2-O-(9-octadecenoyl)-3-O-(9, 12-octadecadienoyl) glycerol (III), 5 alpha, 8 alpha-epidioxy-24 zeta-methylcholesta-6, 22-dien-3 beta-ol (IV) and 1, 6, 8-trihydroxyl-3-methyl-9, 10-anthracenedione (V), were isolated from the mycelium of Penicillium thomii. CONCLUSION: Penicillixanthone A is a new compound, while the others are isolated from Penicillium thomii for the first time. |
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| Keywords: | fungus Penicillium thomii penicillixanthone A |
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