营养治疗途径对急性胰腺炎患者胰床感染的影响

目的探讨重症急性胰腺炎时营养治疗途径对胰床感染的影响。方法３８例急性胰腺炎患者随机分成全胃肠道外营养（ＴＰＮ）２３例，及全肠内营养（ＴＥＮ）１５例两组，对其胰床感染及肠道细菌移位情况进行观察。结果ＴＰＮ组胰床感染率５７１％，而ＴＥＮ组仅为１６７％，胰床感染病例肠系膜淋巴结细菌易位率达８５７％，远高于非胰床感染者（３１６％）（Ｐ＜０．０５）。结论胰床感染菌源自于肠道。胰腺炎患者早期行肠内营养对预防胰床感染及其并发症的发生具有重要作用。

The influence of TPN and TEN on the pancreatic infection in the patient with severe acute pancreatitis

Objective To inverstigate the influence of TPN and TEN on the pancreatic infection in patients with severe acute pancreatitis(SAP). Methods A total of 38 patients with SAP were divided into two groups randomly; TPN group ( n =23) and TEN group ( n =15). Pancreatic infection and intestinal bacterial translocation were observed. Results Pancreatic infection occurred in 57.1% of patients in TPN group, while only 16.7% in TEN group ( P <0.05). The rate of intestinal bacterial translocation of patients suffered pancreatic infection (85.7%) is significantly higer in patients with infection than that in non infection patients (31.6%). Conclusions The bacteria of pancreatic infection are derived from the gut and early enteral nutrition plays an important role in preventing pancreatic infection.