A case of erythroleukaemia with homogeneously staining regions on chromosomes |
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| Authors: | Y.S. Li G. Khalid J.G. Matthews F.G.J. Hayhoe |
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| Affiliation: | Department of Haematological Medicine, University Clinical School, Cambridge, U.K. |
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| Abstract: | A case of erythroleukaemia with homogeneously staining regions on chromosomes is described. The number of chromosomes in bone marrow cells varied from 41 to 46 with a mode of 43. A variety of structural and numerical chromosomal abnormalities was observed. Two marker chromosomes with homogeneously staining regions were found in all aneuploid cells examined. Intensive chemotherapy failed to induce a remission and the patient died 3.9 months after diagnosis. The relation of the homogeneously staining regions on chromosomes to the two courses of chemotherapy prior to cytogenetic study is discussed. |
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| Keywords: | Author Keywords: Chromosomes leukaemia homogeneously staining regions (HSR) |
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