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Tropane alkaloids from <Emphasis Type="Italic">Erythroxylum emarginatum</Emphasis>
Authors:Yumi Nishiyama  Masataka Moriyasu  Momoyo Ichimaru  Maki Sonoda  Kinuko Iwasa  Atsushi Kato  Francis D Juma  Simon G Mathenge  Patrick B Chalo Mutiso
Institution:(1) Natural Medicinal Chemistry, Kobe Pharmaceutical University, 4-19-1, Motoyamakita-machi, Higashinada-ku, Kobe 658-8558, Japan;(2) Department of Clinical Pharmacology, Kenyatta National Hospital, University of Nairobi, P.O. Box 19676, Nairobi, Kenya;(3) Department of Botany, University of Nairobi, P.O. Box 30197, Nairobi, Kenya
Abstract:A tropane alkaloid, anhydroecgonine methyl ester N-oxide (2), was isolated for the first time as a naturally occurring compound, with anhydroecgonine methyl ester (1) from the bark of Erythroxylum emarginatum. Compound 1 was also isolated from the twigs. Their structures were elucidated mainly by spectroscopic methods.
Keywords:Erythroxylum                 emarginatum                Tropane alkaloid  Anhydroecgonine methyl ester N-oxide  Anhydroecgonine methyl ester
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