| 肺炎克雷伯杆菌耐碳青霉烯类的机制及其防治 |
| |
| 引用本文： | 朱亚萍,刘荣玉. 肺炎克雷伯杆菌耐碳青霉烯类的机制及其防治[J]. 国际呼吸杂志, 2011, 31(2): 125-128. DOI: 10.3760/cma.j.issn.1673-436X.2011.002.012 |
| |
| 作者姓名： | 朱亚萍 刘荣玉 |
| |
| 作者单位： | 安徽医科大学第一附属医院老年呼吸内科,合肥,230032 |
| |
| 摘 要： | 近年来耐碳青霉烯类抗生素的肺炎克雷伯杆菌有逐年增多的趋势,其机制主要是碳青霉烯酶的产生,其中又以肺炎克雷伯杆菌碳青霉烯酶最为多见,高产C类头孢菌素酶或超广谱β-内酰胺酶同时合并膜孔蛋白的缺失也逐渐得到重视.耐碳青霉烯类肺炎克雷伯杆菌的控制面临严峻的考验,目前提倡防治相结合的综合措施,积极加强医院管理,严格感染控制措施,...
|
| 关 键 词： | 肺炎克雷伯杆菌 膜孔蛋白 肺炎克雷伯杆菌碳青霉烯酶 防治措施 |
Mechanism and control measures of carbapenem-resistant Klebsiella pneumoniae |
| |
| ZHU Ya-ping,LIU Rong-yu. Mechanism and control measures of carbapenem-resistant Klebsiella pneumoniae[J]. International Journal of Respiration, 2011, 31(2): 125-128. DOI: 10.3760/cma.j.issn.1673-436X.2011.002.012 |
| |
| Authors: | ZHU Ya-ping LIU Rong-yu |
| |
| Abstract: | In recent years, carbapenem-resistant Klebsiella pneumoniae is increasing year by year.The main mechanism is the production of carbapenemase, especially Klebsiella pneumoniae carbapenemase,highly producing class C cephalosporinase or superspectrum β-lactamase combined with loss of membrane protein is another important mechanism. The control of carbapenem-resistant Klebsiella pneumoniae is faced with a severe test. Recently,it is advocated that combination measures of prevention and treatment,actively strengthening hospital management, strictly making infection control measures,sensitive drug treatment, and multi-drug combination therapy. This article discusses the mechanism and control measures of carbapenem-resistant Klebsiella pneumoniae. |
| |
| Keywords: | Klebsiella pneumoniae Membrane protein Klebsiella pneumoniae carbapenemase Control measures |
| 本文献已被 万方数据 等数据库收录！ |
|
