| 成人腺泡状横纹肌肉瘤11例临床病理学分析 |
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| 引用本文： | 徐傲,陈柯,吴海波,王晓秋. 成人腺泡状横纹肌肉瘤11例临床病理学分析[J]. 安徽医药, 2011, 15(2): 183-185 |
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| 作者姓名： | 徐傲 陈柯 吴海波 王晓秋 |
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| 作者单位： | 安徽医科大学附属省立医院病理科,安徽,合肥,230001;安徽医科大学附属省立医院病理科,安徽,合肥,230001;安徽医科大学附属省立医院病理科,安徽,合肥,230001;安徽医科大学附属省立医院病理科,安徽,合肥,230001 |
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| 摘 要： | 目的探讨成人腺泡状横纹肌肉瘤(alveolar rhabdom yosarcoma,ARMS)的临床病理学特征、免疫表型和鉴别诊断。方法回顾性分析11例成人ARMS的临床资料、病理学形态和免疫组化标记结果。结果 11例患者中7例女性,4例男性。年龄19～60岁,平均41岁。组织学上可见特征性的腺泡状结构,9例经典型均可见部分的实体性区域。1例实体型者由一致的实性细胞巢组成,不见腺泡状结构。1例胚胎性-腺泡状混合型在经典的ARMS的局部区域可见胚胎性横纹肌肉瘤的形态。免疫组化标记显示瘤细胞均表达myogenin、CD56、Vimentin多数表达Syn(66.7%)、S100(55.6%)、CD99(50%)、desmin(87.5%)、MyoD1(33.3%),均不表达CK、CD45。术后随访6个月～3年,4例死亡,3例复发。结论成人ARMS少见,男女均好发,头颈部是最好发部位,具有较强的侵袭性行为。形态学上应于多种小圆细胞肿瘤及透明细胞肿瘤相鉴别。
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| 关 键 词： | 横纹肌肉瘤 病理学 腺泡状 |
Alveolar rhabdomyosarcoma in adults: a clinicopathologic analysis of 11 cases |
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| XU Ao,CHEN Ke,WU Hai-bo,WANG Xiao-qiu. Alveolar rhabdomyosarcoma in adults: a clinicopathologic analysis of 11 cases[J]. Anhui Medical and Pharmaceutical Journal, 2011, 15(2): 183-185 |
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| Authors: | XU Ao CHEN Ke WU Hai-bo WANG Xiao-qiu |
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| Affiliation: | XU Ao,CHEN Ke,WU Hai-bo,WANG Xiao-qiu(Department of Pathology,Affiliated Provincial Hospital,Anhui Medical University,Hefei 230001,China) |
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| Abstract: | Aim To study the clinicopathological features,immunophenotype and differential diagnosis of alveolar rhabdomyosarcoma in adults(ARMS).Methods The clinical,pathologic and immunohistochemical features were evaluated in 11 cases of ARMS in adults.Results 11 cases of ARMS in adults were retrieved from the pathological archive of this hospital.7cases were female,4 cases male,age ranging from 19 to 60 years(median,41 year).Histologically,all the tumors were mainly composed of classic form.In the classic form,it c... |
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| Keywords: | rhabdomyosarcoma pathology alveolar |
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