基因治疗载体的研究现状

基因治疗是随着现代分子生物学技术的发展而诞生的一种生物医学治疗技术，主要涉及载体、目的基因和靶细胞三方面。将目的基因导入靶细胞，得到稳定高效的表达是基因治疗的关键问题，因而选择合适的载体是基因治疗成功的基础。目前应用的载体主要包括病毒载体和非病毒载体两类，此文就近几年来有关基因治疗载体的研究作一简要综述。

Current status of gene therapy vector research

Gene therapy is a biomedical treatment technology emerging with the development of modern molecular biology, which involves three aspects: vector, target gene and target cell. The key point of gene therapy is transferring target gene to target cell and obtaining stable and high efficiency expression. Therefore, selecting compatible vector is the basis of the success in gene therapy. Vectors for gene therapy used at present mainly include viral vectors and non-viral vectors. This article reviews researches of vectors for gene therapy in recent years.