火绒草中酚类成分的分离与鉴定

目的对火绒草的化学成分进行分离与鉴定。方法应用硅胶柱色谱、葡聚糖凝胶柱色谱和高效液相制备色谱分离纯化,根据理化性质和波谱数据确定化合物的结构。结果从火绒草中分离得到10个化合物,分别鉴定为咖啡酸乙酯(ethyl caffeate,1)、芹菜素(apigenin,2)、对羟基苯甲酸(P-hydroxybenzoic acid,3)、原儿茶醛(protocatechuic aldehyde,4)、原儿茶酸(protocatechuic acid,5)、咖啡酸(caffeic acid,化合物6)、槲皮素(quercetin,7)、木犀草素(luteolin,8)、对羟基桂皮酸(p-hydroxy cinnamic acid,9)、阿魏酸(ferulic acid,10)。结论化合物1-3、8首次从火绒草中分离得到,化合物1-3为首次从火绒草属植物中分离得到。

Isolation and identification of phenols constituents from Leontopodium leontopodioid

Objective To isolate and identify the chemical constituents from Leontopodium leontopodioid. Methods Compounds were isolated and purified on the silica gel, sephadex LH-20 chromatograph and RP-HPLC. The structures of chemical compounds were elucidated on the basis of spectra data. Results Ten compounds were identified as ethyl coffee(1), apigenin(2), p-hydroxybenzoic acid(3), protocatechuic aldehyde(4), protocatechuic acid(5), caffeic acid(6), quercetin(7), luteolin(8), hydroxy cinnamic acid(9) and ferulic acid(10), respectively. Conclusions Compounds 1-3, 8 are isolated from Leontopodium leontopodioid for the first time, and compounds 1-3 are purified from Leontopodium for the first time.