漯河市中老年人群类风湿关节炎与慢性肾脏病流行病学调查

目的 了解漯河市中老年类风湿关节炎(RA)患者人群慢性肾脏病(CKD)流行病学现况.方法 采用分层整群抽样的的方法,抽取漯河市中老年(≥45岁)居民3266人,进行问卷调查、体格检查、肾脏损伤及RA专项检测.按结果分为RA组和非RA组.结果 3072名资料完整居民中,RA及可疑患者的患病率为6.90％,蛋白尿、血尿和eGFR下降的发生率分别为10.42％、8.59％和1.82％.与非RA组比较,RA组患者蛋白尿、eGFR下降发生率升高(分别为14.62％比10.10％,4.72％比1.61％,均P＜0.05).两组血尿发生率差异无统计学意义(10.85％比8.43％,P=0.225).本组人群中CKD的总体患病率为16.93％,RA组CKD患病率显著高于非RA组(22.17％比16.54％,P＜0.05).结论 漯河市中老年人群CKD患病率较高,RA患者人群有其特殊流行病学特征.

Epidemiology investigation on rheumatoid arthritis and chronic kidney disease among population older than 45 years in Luohe city

Objective To study the prevalence of chronic kidney disease (CKD) among population with rheumatoid arthritis(RA) in Luohe city. Methods 3072 residents (older than 45 years) with eligible data from Luohe city were randomly selected using a stratified, multistage sampling. All residents were interviewed and given physical examination, tested for sample of uria and blood, and also given special examination about RA. Results The prevalence of RA was 6.90% in 3072 subjects. The albuminuria was detected in 10.42% of subjects, hematuria in 8.59%, reduced renal function in 1.82%, Howerer, which was higher in patients with RA, was 14.62%, 10.85% and 4.72% respectively. Especially the prevalence of albuminuria and reduced renal function in RA patients was significantly higher compared to that in population without RA(14.62% vs 10.10%, P＜0.05 and 4.72% vs 1.61%, P＜0.01), but no significant differences in hematuria(10.85% vs 8.43%, P＞0.05). The prevalence of CKD was 16.93% in tougher, and RA patients had higher prevalence of CKD than those population without RA(22.17% vs 16.54%, P＜0.05). Conclusion The prevalence of CKD among population older than 45 years in Luohe city is high, and the patients with RA have special characteristic in epidemiology of CKD.