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Complete atrioventricular block induced by rituximab in monotherapy in an aged patient with non-Hodgkin’s diffuse large B-cell lymphoma
Authors:José Manuel Cervera Grau  Gaspar Esquerdo Galiana  Ana Belso Candela  Cristina Llorca Ferrándiz  Asunción Juárez Marroquí  Sonia Maciá Escalante
Institution:Oncology Department, Hospital General de Elda, Elda, Alicante, Spain. cerveragrau@yahoo.es
Abstract:Rituximab is a treatment option to non-Hodg kin's diffuse large B-cell lymphoma (NHDLBCL) in advanced stage and comorbility. It is known the cardiotoxicity effect of this drug, but there is no previous report describing a complete atrioventricular block (CAVB) secundary to treatment with Rituximab. We present an elderly woman treated with monotherapy with Rituximab who experienced a CAVB after administration of the fifth dose of this drug.
Keywords:Non-Hodgkin’  s lymphoma  Cardiac block  Rituximab
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