| 锰超氧化物岐化酶模型配合物的研究 |
| |
| 引用本文： | 胡智华,梅光泉. 锰超氧化物岐化酶模型配合物的研究[J]. 现代医学, 1994, 0(2) |
| |
| 作者姓名： | 胡智华 梅光泉 |
| |
| 作者单位： | 南京铁道医学院化学教研室，南京大学配位化学研究所 |
| |
| 摘 要： | 为探索天然超氧化物岐化酶（ＳＯＤ）岐化超氧离子的机理，及用于临床的可能性，我们合成了乳酸、柠檬酸和酒石酸的锰（Ⅱ）配合物作为Ｍｎ－ＳＯＤ的模拟物，用光照法测定了它们的活性，得到了有意义的结果：锰配合物作为Ｍｎ－ＳＯＤ的模拟物，有肯定的活性，其中以乳酸锰配合物活性最高。
|
| 关 键 词： | 氧化还原酶类，锰，甲荃马来酸 |
Study on Simulated Complexes of Mn Superox-icd Dismutase |
| |
| Hu Zhihua,Mei Guangquan,Teaching and Research Section of Chemistry,Nanjing Railway Medical College,Nanjing. Study on Simulated Complexes of Mn Superox-icd Dismutase[J]. Modern Medical JOurnal, 1994, 0(2) |
| |
| Authors: | Hu Zhihua Mei Guangquan Teaching Research Section of Chemistry Nanjing Railway Medical College Nanjing |
| |
| Affiliation: | Hu Zhihua,Mei Guangquan,Teaching and Research Section of Chemistry,Nanjing Railway Medical College,Nanjing,210009 |
| |
| Abstract: | n order to research for the dismutationmechanisin of superoxide from natural super-oxide dismutase (SOD) and the clinical signif-icance of SOD mimics the SOD activity of syn-thesized nianganese ( I ) complexes of lacticacid, citric acid and tartaric acid wee deter-'nined and significant results obtained. Thestudy sbowed that the three manganese coni-plexes have affirniative SOD activity with thesequence of Mn (II) lactate>Mn (II) citrate>Mn (II) tartarate. |
| |
| Keywords: | oxidoreductasesmanganese citraconic acid |
| 本文献已被 CNKI 等数据库收录！ |
