| 托盘根乙醇提取物对淋巴细胞转化及IL-2产生的影响 |
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| 引用本文： | 徐颖,杜钢军,牟孝硕,孙朋悦,张宝凤,胡晓芳. 托盘根乙醇提取物对淋巴细胞转化及IL-2产生的影响[J]. 沈阳药科大学学报, 2000, 17(6): 438-440 |
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| 作者姓名： | 徐颖 杜钢军 牟孝硕 孙朋悦 张宝凤 胡晓芳 |
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| 作者单位： | 沈阳药科大学药学系沈阳 110015 |
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| 摘 要： | 作者选用C57BL/6J小鼠、老龄小鼠和环磷酰胺 (CY)所致免疫功能低下小鼠模型 ,观察了托盘根乙醇提取物 (ERC)对正常小鼠、老龄小鼠和CY鼠淋巴细胞转化及IL 2生成的影响 .ERC40 0 μg/mL可促进正常小鼠的淋巴细胞转化功能 ;ERC 40 0、2 0 0、10 0 μg/mL对老龄小鼠的淋巴细胞转化有明显的促进作用 ;ERC 40 0、2 0 0 μg/mL对CY所致的免疫功能低下小鼠的淋巴细胞转化也有促进作用 .同时作者还观察到ERC 40 0 μg/mL能增加正常小鼠脾淋巴细胞IL 2的生成 ;ERC40 0、2 0 0、10 0 μg/mL对老龄小鼠脾淋巴细胞IL 2的生成均有促进作用 .
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| 关 键 词： | 托盘根乙醇提取物 老龄鼠 CY鼠 淋巴细胞转化 IL2 |
| 修稿时间： | 1999-12-28 |
The Effects of ERC on Spleen Lymphocyte Transformation and IL-2 Production |
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| Xu Ying,Du Gangjun,Mu Xiaoshuo,Sun Pengyue,Zhang Baofeng,Hu Xiaofan. The Effects of ERC on Spleen Lymphocyte Transformation and IL-2 Production[J]. Journal of Shenyang Pharmaceutical University, 2000, 17(6): 438-440 |
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| Authors: | Xu Ying Du Gangjun Mu Xiaoshuo Sun Pengyue Zhang Baofeng Hu Xiaofan |
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| Affiliation: | Xu Ying,Du Gangjun,Mu Xiaoshuo,Sun Pengyue,Zhang Baofeng,Hu Xiaofan Department of Pharmacy,Shenyang Pharmaceutical University,Shenyang 110015 |
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| Abstract: | The effects of ERC(extract of Rubus crataegifolius )on spleen lymphocyte transformation and IL-2 production of normal mice,aged mice and CY-treated mice were observed.The results indicated that ERC 400 μg/mL improved lymphocyte transformation of normal mice,that ERC 400,200,100 μg/mL increased the transformed rate of aged mice,and that ERC 400,200 μg/mL also improved lymphocyte transformation of CY-treated mice.Meanwhile,the results also indicated that ERC 400 μg/mL could enhance IL-2 production of normal mice,and that ERC 400,200,100 μg/mL could increased the IL-2 production of aged mice. |
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| Keywords: | extract of Rubus crataegifolius aged mice CY-treated mice lymphocyte transformation IL-2 |
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