慢性心衰与正常甲状腺功能病态综合征的关系(附47例分析)

目的探讨慢性心衰与正常甲状腺功能病态综合征(ESS)的关系。方法采用时间分辨荧光免疫分析法检测47例慢性心衰患者(心衰组)与30例健康者(对照组)TT3、TT4、FT3、FT4及TSH水平。结果心衰组较健康组血清TT3、FT3明显降低(P<0.05),不同心功能患者差异亦具统计学意义(P<0.05),各组血清TT4、FT4、TSH差异无统计学意义;心衰纠正前后TT3、FT3值比较具有统计学差异(P<0.05),而血清TT4、FT4、TSH差异无统计学意义。结论慢性充血性心衰患者常合并ESS,它与心衰的严重程度相关;ESS应是慢性心衰的伴随症状,为机体的适应性反应。

The Relationship Between Congestive Heart Failure and Euthyroid Sick Syndrome: A Report of 47 Cases

Objective To explore the relationship between congestive heart failure(CHF) and euthyroid sick syndrome.Methods Serum thyroid levels(TT3,TT4,FT3,FT4 and TSH) in 47 patients with CHF and 30 normal persons(controls) were determined by time resolved fluoro-immunoassay.Results The levels of serum triiothyronine and free triiothyronine in the group of CHF were significantly lower that in controls(P<0.05);There were significant differences in the varies of heart function between two groups(P<0.05);The changes of serum thyroxine,free thyroxine and thyroid-stimulating hormone had not significant difference between 2 groups.Conclusoins The patients with CHF usually is accompanied with euthyroid sick syndrome.It can be used to estimate the prognosis in patients with CHF.Euthyroid sick syndrome may be a simultaneous phenomenon of heart failure,which will be an adaptation reaction to organism in the condition.