Abstract: | Sixty patients with acute ischemic cerebral infarction within 72 h were equally divided into 2groups.The nimodipine group 30 patients(M 21,F 9;age 59±s10 a) received nimodipine 2 mg/d intravenous infusion based on supported therapy(dehydrant,vit C)in 1-2 wk,oral nimodipine 60 mg every evening in 1-4 wk.Supported therapy was altered to improve hemodilution,microcirculation,and nervous cell activator in 3-4wk.Control group 30 patients(M23,F7,age 58±9 a) received only supported therapy.Irrespective of condition of patients or size of infarction, nervous functional defect scores of the nimodipine group decreased more than those of the control group(P<0.01).The effects of nimodipine showed no difference between those within 30h after onset and those within 31-72h. |