| 直肠癌新辅助放化疗的适宜人群及疗效评价 |
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| 引用本文： | 申丽君,章真. 直肠癌新辅助放化疗的适宜人群及疗效评价[J]. 中华胃肠外科杂志, 2014, 0(3): 201-205 |
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| 作者姓名： | 申丽君 章真 |
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| 作者单位： | 复旦大学附属肿瘤医院放疗科复旦大学上海医学院肿瘤学系,200032 |
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| 基金项目： | 国家自然科学基金（81372432）;复旦大学“985工程”三期放射医学研究（985IIIYPT06） |
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| 摘 要： | 新辅助放化疗联合根治性手术是局部进展期直肠癌[T3～T4和（或）N1～N2]的标准治疗模式，20％左右的患者能获得病理完全缓解及更好的预后。选择出真正适合放化疗的患者有利于指导其个体化治疗，避免治疗过度。对放化疗后的疗效进行评价有助于下一步治疗方案的确立，影像学及病理学评价仍是目前最为主要的评价方式。
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| 关 键 词： | 直肠肿瘤 新辅助放化疗 预测 |
Patients selection and response evaluation in neoadjuvant chemoradiation of rectal cancer |
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| Shen Lijun,Zhang Zhen. Patients selection and response evaluation in neoadjuvant chemoradiation of rectal cancer[J]. Chinese journal of gastrointestinal surgery, 2014, 0(3): 201-205 |
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| Authors: | Shen Lijun Zhang Zhen |
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| Affiliation: | . Department of Radiation Olwology, Cancer Hospital, Fudan University, Department of Oncology , Shanghai Mediccd College, Fudan University, Shanghai 200032, China |
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| Abstract: | Neoadjuvant chemoradiation combined with radical surgery has been established as the standard care for locally advanced rectal cancer （T3-T4 and/or N1-N2）. Approximately 20% patients who achieve complete pathological response have an improved prognosis. Appropriate patient selection may help avoid over-treatment. Evaluation of treatment response mostly with imaging study and pathology after neoadjuvant chemoradiation and following surgery is essential for the subsequent selection of treatment strategy. |
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| Keywords: | Rectal neoplasms Neoadjuvantchemoradiation Prediction |
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