| 甲基维生素B_（12）、维生素B_（12）降低甲基汞含量及免疫与行为毒性作用的研究 |
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| 引用本文： | 陈炳卿,孙长颢,任莹,邱隽,赵秀娟,石华.甲基维生素B_（12）、维生素B_（12）降低甲基汞含量及免疫与行为毒性作用的研究[J].卫生研究,1995(Z2). |
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| 作者姓名： | 陈炳卿 孙长颢 任莹 邱隽 赵秀娟 石华 |
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| 作者单位： | 哈尔滨医科大学公共卫生学院，黑龙江省食品卫生监督检验所 |
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| 摘 要： | 研究发现２．０～３．０ｍｇ／ｋｇ甲基维生素Ｂ_（１２）、维生素Ｂ_（１２）均可使孕鼠脑、肝、肾中甲基汞含量明显低于甲基汞组，而对胎仔脑及胎盘中甲基汞含量有明显减少。甲基维生素Ｂ_（１２）、维生素Ｂ_（１２）并可增强机体特异性细胞免疫功能与机体非特异性免疫功能，可改善动物多种行为不良作用。
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| 关 键 词： | 甲基维生素B_（12），维生素B_（12），甲基汞含量，免疫，行为 |
Effect of methylcobalamin and vitamin B_(12) on the contents of methylmercury,immune toxicity and behavioral teratogenesis caused by methylmercury in rats |
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| Chen Bingqing,Sun Changhao,Ren ying,Qiu Jun,et al..Effect of methylcobalamin and vitamin B_(12) on the contents of methylmercury,immune toxicity and behavioral teratogenesis caused by methylmercury in rats[J].Journal of Hygiene Research,1995(Z2). |
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| Authors: | Chen Bingqing Sun Changhao Ren ying Qiu Jun |
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| Abstract: | Theresults showcdthat at thedose of 2.0～3.0mg/kg,both methylcobdamin and vitamin B12 reduced the content of methylmercury in the brains, livers and kindneys in pregnant rats; but in their offsprings, the reduction was found only in the brains and placentas, The results also indicated that methylcobalamin and vitamin B12 could improve the specific and non-specific immune function , and the abnormal behaviors of rats. |
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| Keywords: | methylcobalamin vitamin B_(12) methylmercury content immunity behavior |
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