Isolation and mapping of a polymorphic CA repeat sequence at the human VRK1 locus |
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| Authors: | Jun Sugimoto Toshihiro Yamauchi Toyomasa Hatakeyama Masaharu Isobe J. Sugimoto T. Yamauchi T. Hatakeyama M. Isobe |
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| Affiliation: | (1) Molecular and Cellular Biology Laboratory, Department of Materials and Biosystem Engineering, Faculty of Engineering, Toyama University, 3160 Gofuku, Toyama City 930-8555, Japan Tel. +81-764-45-6872; Fax +81-764-45-6874 e-mail: isobe@ng.toyama-u.ac.jp, JP |
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| Abstract: | VRK1 is a novel human putative serine/threonine kinase, and is located on chromosome 14 at band q32 where an autosomal recessive congenital microphthalmia (CMIC) is mapped. We isolated a polymorphic dinucleotide CA repeat marker from a genomic clone containing the human VRK1 gene. This polymorphism will be useful in genetic studies of disorders localized at the 14q32 region, such as CMIC. Received: October 8, 1998 / Accepted: October 16, 1998 |
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| Keywords: | CA repeat VRK1 gene Congenital micro-phthalmia (CMIC) |
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