97例肺癌合并上腔静脉综合征的治疗分析

目的 回顾分析肺癌合并上腔静脉综合征的治疗方式,以探讨最佳治疗方法。方法将97例患者分为二组,先行放疗组51例和先行化疗组46例。其中,先放疗组分冲击放疗组12例和常规放疗组39例,然后比较分析。结果 先行放疗者完全缓解率为72.6％,明显高于先行化疗者(26％,P<0.01)。放射治疗组中,接受冲击放疗者7 d内症状缓解率(50％)高于常规放疗者(28.2％,P<0.05)。结论 在肺癌合并SVCS的治疗中,冲击放疗是最佳治疗方法。

Management of superior vena cava syndrome in lung cancer:analysis of 97 patients

Objective To explore the best treatment method for lung cancer complicated with superior vena cava syndrome(SVCS) .Methods The treatment methods of 97 patients were retrospectively analyzed by dividing them into two groups: 51 patients were given radiotherapy firstly (first group) and 46 patients were given chemotherapy firstly(second group) . In the first group, 12 patients with high dose fractions and 39 patients with conventional fractions.Results Complete response rate of SVCS was 72.6% in the first group and 26% in the second group( P < 0.01). In the first group, symptomatic relief of SVCS within 7 days was obtained in 50 % patients with high dose fractions and in 28.2% patients with conventional fractions(P < 0.05) .Conclusion Radiotherapy with high dose fractions was the best way in treatment of lung cancer with SVCS.