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联合P504s/P63检测应用于前列腺癌诊疗的价值
引用本文:赛利佛,张孝斌,程帆,余伟民. 联合P504s/P63检测应用于前列腺癌诊疗的价值[J]. 武汉大学学报(医学版), 2011, 32(3): 378-380,404,插页4
作者姓名:赛利佛  张孝斌  程帆  余伟民
作者单位:武汉大学人民医院泌尿外科,湖北武汉,430060
摘    要:目的:探讨联合P504s/P63免疫组化对前列腺癌诊断准确度改善及其临床预后价值.方法:采用免疫组化对3个组(前列腺癌、上皮内瘤、良性前列腺增生)标本的P504s/P63表达进行检测并比较;评估前列腺癌诊断准确度,分析前列腺癌组P504s表达与3个临床预后因素(前列腺特异性抗原水平,Gleason评分及临床疾病分期)之...

关 键 词:前列腺癌  上皮内瘤  良性前列腺增生  P504s  P63

Application Value of Cocktail P504s/P63 Immunohistochemistry in Prostate Cancer Diagnosis and Treatment
Salifou Issiaka Traore,ZHANG Xiaobin,CHENG Fan,YU Weimin. Application Value of Cocktail P504s/P63 Immunohistochemistry in Prostate Cancer Diagnosis and Treatment[J]. Medical Journal of Wuhan University, 2011, 32(3): 378-380,404,插页4
Authors:Salifou Issiaka Traore  ZHANG Xiaobin  CHENG Fan  YU Weimin
Affiliation:Salifou Issiaka Traore,ZHANG Xiaobin,CHENG Fan,YU Weimin Dept.of Urology,Renmin Hospital of Wuhan University,Wuhan 430060,China
Abstract:Objective: To evaluate the utility of cocktail P504s/P63 immunohistochemistry(IHC) staining in prostate cancer(Pca) diagnosis and its clinical prognostic significance.Methods: P504s/P63 expression of 93 prostatic specimens were analyzed from 33 cases of Pca,30 cases of prostatic intraepithelial neoplasia(PIN),and 30 cases of benign prostatic hyperplasia(BPH).The relationship between P504s/P63 expression and the three prognostic factors as patient's prostate specific antigen(PSA) levels,Gleason score and cli...
Keywords:Prostate Cancer  Prostatic Intraepithelial Neoplasia  Benign Prostatic Hyperplasia  P504s  P63  
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