| Snail和E-cadherin在上皮性卵巢癌组织中的表达及其与上皮-间叶转化的关系 |
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| 引用本文： | 郑艳萍,姚爱香,鄢学菊. Snail和E-cadherin在上皮性卵巢癌组织中的表达及其与上皮-间叶转化的关系[J]. 武汉大学学报(医学版), 2011, 32(3): 385-387,后插1 |
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| 作者姓名： | 郑艳萍 姚爱香 鄢学菊 |
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| 作者单位： | 湖北省荆门市第一人民医院妇产科,湖北荆门,448000 |
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| 摘 要： | 目的:探讨上皮-间叶细胞转变(EMT)的标记分子Snail和E-cadherin在上皮性卵巢癌组织中的表达及其与卵巢癌恶性生物学行为的相关性.方法:采用免疫组化方法分别检测45例卵巢上皮性癌组织中Snail和Ecadherin的表达状况,并分析其与卵巢癌主要临床病理参数之间的关系.结果:45例卵巢癌组织中Snail阳性...
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| 关 键 词： | 卵巢肿瘤 Snail E-cadherin 上皮-间叶转化 |
Expression of Snail and E-cadherin in Epithelial Ovarian Cancer and Their Relationship with Epithelial-Mesenchymal Transition |
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| ZHENG Yanping,YAO Aixiang,YAN Xueju. Expression of Snail and E-cadherin in Epithelial Ovarian Cancer and Their Relationship with Epithelial-Mesenchymal Transition[J]. Medical Journal of Wuhan University, 2011, 32(3): 385-387,后插1 |
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| Authors: | ZHENG Yanping YAO Aixiang YAN Xueju |
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| Affiliation: | ZHENG Yanping,YAO Aixiang,YAN Xueju Dept.of Gynecology and Obstetrics,The First People's Hospital of Jingmen,Jingmen 448000,China |
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| Abstract: | Objective: To investigate the expression of epithelial-mesenchymal transition(EMT) related markers Snail and E-cadherin proteins in epithelial ovarian carcinoma and their relationship with the malignant features.Methods: The expression of Snail and E-cadherin proteins was detected in 45 cases of epithelial ovarian cancer by immunohistochemistry method and its relationship with clinic pathological data was also analyzed.Results: Snail positive expression rate was 40%(18/45) in 45 cases of ovarian cancer,whil... |
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| Keywords: | Ovarian Neoplasms Snail E-cadherin Epithelial-Mesenchymal Transition |
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