| 祛异康对子宫内膜异位症模型大鼠血清FSH、LH、E2、P的影响 |
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| 引用本文： | 杨鉴冰,刘晓倩. 祛异康对子宫内膜异位症模型大鼠血清FSH、LH、E2、P的影响[J]. 现代中医药, 2011, 31(4): 66-67,76 |
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| 作者姓名： | 杨鉴冰 刘晓倩 |
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| 作者单位： | 1. 陕西中医学院,陕西,咸阳,712046
2. 高陵县人民医院,陕西,高陵,710200 |
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| 基金项目： | 陕西省教育厅自然科学专项课题 |
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| 摘 要： | 目的观察祛异康对子宫内膜异位症模型FSH、LH、E2、P的影响,探讨其治疗子宫内膜异位症的作用机理。方法采用手术移植法建立大鼠子宫内膜异位症模型,随机分为对照组、模型组、祛异康组、丹那唑组。造模成功各组给药4 W,放射免疫法检测血清FSH、LH、E2、Pα的含量。结果与模型组比较祛异康组、丹那唑组具有明显降低异位症大鼠血清中E2的含量(P<0.05);升高LH、P水平(P<0.05)。结论祛异康能明显抑制异位症模型大鼠异位内膜的生长,增加妊娠率,其治疗机理可能是通过抑制内异症大鼠血清E2的异常分泌,提高LH、P含量而起到抑制异位内膜的生长,恢复内分泌功能,减轻患者临床症状,达到治疗內异症的目的 。
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| 关 键 词： | 子宫内膜异位症 FSH LH E2 P 中药祛异康 实验研究 |
The Effects of Quyikang on Serum FSH,LH,E2 and P of Rats with Endometriosis |
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| Yang Jianbing,Liu Xiaoqian. The Effects of Quyikang on Serum FSH,LH,E2 and P of Rats with Endometriosis[J]. Modern Traditional Chinese Medicine, 2011, 31(4): 66-67,76 |
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| Authors: | Yang Jianbing Liu Xiaoqian |
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| Affiliation: | Yang Jianbing1 Liu Xiaoqian2(1.Shaanxi University of Chinese Medicine,Xianyang,Shaanxi,712046,2.People's Hospital of Gaoling County,Gaoling,710200) |
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| Abstract: | Objective: To observe the effects of Quyikang on FSH,LH,E2 and P of endometriosis model,and to investigate its mechanism in the treatment of endometriosis.Methods: Rats model of endometriosis was built by surgical transplant,and were randomly divided into the control group,model group,Quyikang group and Danazol group.After successful modeling,each group was given medicine for 4 weeks.The content of serum FSH,LH,E2 and P were determined with radioimmunoassay.Results: Compared with the model group,the content... |
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| Keywords: | FSH LH E2 P |
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