联合吸入治疗慢性阻塞性肺病稳定期患者的疗效观察

目的 观察联合吸入异丙托溴铵气雾剂和沙美特罗/替卡松粉吸入剂对慢性阻塞性肺病(COPD)稳定期患者的疗效.方法 采用随机、盲法、平行对照研究.将80例COPD患者随机分为观察组和对照组,疗程24周.观察组给予异丙托溴铵气雾剂和沙美特罗/替卡松粉吸入剂治疗,对照组给予异丙托溴铵气雾剂治疗.分别对两组患者治疗前后的临床症状...

The curative effects of ipratropium bromide inhalation aerosol combined with salmeterol fluticasone propionate inhalation powder on chronic obstructive pulmonary disease patients in stable phase

Objective To observe the effect of ipratropium bromide inhalation aerosol combined with salmeterol fluticasone propionate inhalation powder on chronic obstructive pulmonary disease（COPD） patients in stable phase.Methods A randomized,blinding,parallel control study was used in this study.80 patients with COPD were randomly divided into two groups and treated for 24 weeks.Observation group was treated with ipratropium bromide aerosol and fluticasone salmeterol powder inhalation therapy,while control group was only received ipratropium bromide aerosol.The effects of two therapeutic plans were evaluated by the clinical symptom score（SGRQ） and pulmonary function testing.Results After treatment,two groups SGRQ scores were lower than before,and the score of observation group was significantly lower than that of control group（P0.05）.FEV1/FVC,the percentage of Forced expiratory volume in 1 second（FEV1） percentage of predicted value（FEV1%） of two groups were shown varying degrees of improvement after treatment,and these data of observation group are better than that of control group（P0.05）.Conclusion Treatment of stable COPD patients by using inhalation aerosol ipratropium bromide and salmeterol fluticasone propionate inhalation powder can not only make their lung function better,but also can improve their exercise tolerance and quality of life.