Acebrophylline-induced angioedema |
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| Authors: | Sanitha Kuriachan Mohan Babu V Amberkar Manu K Mohan Hameed Aboobackar Shahul Meenakumari Kamal Kishore |
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| Institution: | Department of Pharmacology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India;1Department of Pulmonary Medicine, Kasturba Medical College and Hospital, Manipal University, Manipal, Karnataka, India |
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| Abstract: | A 53-year-old woman visited her physician complaining of acute breathlessness and productive cough. Her medications included budesonide and formoterol for asthma, fixed-dose combination aspirin 150 mg + clopidogrel 75 mg + atorvastatin 20 mg for ischemic heart disease. History revealed that she had allergic rhinitis and was hypersensitive to penicillins. The patient was prescribed acebrophylline (ABP). Six hours after ABP therapy she presented with generalized urticarial lesions, swelling of hands, feet, lips and face, suggestive of angioedema. ABP was stopped immediately, and the patient was treated symptomatically. This case was categorized as probable as per standard causality assessment scale.KEY WORDS: Allergic, de-challenge, Naranjo''s scale, urticarial lesions |
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