雾化吸入布地奈德和地塞米松常规治疗小儿急性喉炎并发呼吸困难疗效的对比

目的 探讨雾化吸入布地奈德和地塞米松治疗小儿急性喉炎并呼吸困难的方法及效果。方法 选择本院2018年1月—2019年1月期间收治的小儿急性喉炎并发呼吸困难患儿,共计120例,采用随机数字表法将其分为60例观察组和60例对照组,对照组患儿采用地塞米松治疗,观察组患者采用雾化吸入布地奈德治疗,比较两组患儿的临床疗效、临床症状消失时间以及出现支气管痉挛、呕吐等不良反应情况。结果 治疗后观察组患儿痊愈36例、有效20例、无效4例,总有效率为93.3%,对照组患儿的对应数据分别为27例、20例和13例,治疗有效率为78.3%,低于观察组(P<0.05)。观察组患儿临床症状消失时间和住院时间短于对照组患儿(P<0.05)。结论 与地塞米松常规治疗相比,采用雾化吸入布地奈德治疗小儿急性喉炎并发呼吸困难的临床疗效更好,具有较高的临床应用价值。

Comparison of clinical efficacies between atomized inhalation of budesonide and dexamethasone in treatment of acute laryngitis and dyspnea in children

Objective To study the clinical efficacies of atomized inhalation of budesonide and dexamethasone in the treatment of acute laryngitis and dyspnea in children.Methods A total of 120 children with acute laryngitis and dyspnea were selected in a hospital from January 2018 to January 2019,and they were divided into a trial group and a control group with 60 cases in each group by the random number table method.The children in the control group were treated with dexamethasone,and the patients in the trial group were treated with budesonide inhalation.The clinical efficacies,time of clinical symptom disappearance and adverse reactions,such as bronchospasm and vomiting were observed and compared between the two groups.Results After the treatment,in the trial group,36 cases were cured,20 cases were effective,and 4 cases were ineffective,with the total effective rate of 93.7%.In the control group,27 cases were cured,20 cases were effective,and 13 cases were ineffective,with the total effective rate of 78.3%,which was lower than that of the trial group(P<0.05).In addition,the time of the clinical symptom disappearance and the time hospitalization of the trial group were both shorter than those of the control group(P<0.05).Conclusion Compared with dexamethasone,the clinical efficacy of atomized inhalation of budesonide is better and safer in the treatment of acute laryngitis and dyspnea in children.